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Cervical Cancer

Vaccine may lose effectiveness during ovulation

Published in Cancer Weekly, August 26th, 2003

A new, small study has found that a vaccine against human papillomavirus 16 (HPV16), the virus that causes most cases of cervical cancer, produces antibodies against HPV16 at the site where cervical cancer develops - a promising indication of the vaccine's effectiveness.

But antibody levels appear to decrease around ovulation, raising the possibility that the vaccine may be less effective during that time. The findings appeared in the August 6, 2003, issue of the Journal of the National Cancer Institute.

A vaccine is considered promising if it can produce an immune response (determined by levels of antibodies) at disease-specific sites such as...

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