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Clear Cell Carcinoma

Three immunohistochemical stains help distinguish clear cell cancer as ovarian or renal

Published in Cancer Weekly, September 2nd, 2003

Three immunohistochemical stains can help distinguish clear cell carcinoma origin as ovarian or renal.

According to recent research published in the International Journal of Gynecological Pathology, "The diagnosis of primary clear cell carcinoma of the ovary or kidney is usually straightforward. However, problems in ascertaining the site of the primary tumor may arise when there is widespread metastatic disease or when clear cell carcinoma is present in both the ovary and kidney. In this study, the value of a panel of antibodies in distinguishing between an ovarian and renal clear cell carcinoma was evaluated.

"The panel comprised cytokeratins...

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