Head and Neck Cancer

Endostatin also effective for head and neck cancer

Published in Cancer Weekly, September 2nd, 2003

Researchers at Ohio State have found that endostatin has a dual effect on head and neck cancer cells - the compound prevented the cells from developing new blood vessels and also hindered the mechanism cancer cells use to migrate throughout the body and invade other tissues.

Head and neck cancers originate on the epithelium - the layer of tissue covering the outermost surfaces of the body, including the skin and mucus membranes. Kaposi sarcoma tumors arise from the endothelium, the cells that line blood vessels.

"The vast majority of endostatin studies have concentrated on endostatin's effects against endothelial cells, and haven't focused on the...

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Source: Cancer Weekly (2003-09-02)

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