Cancer Weekly

Hodgkin Lymphoma - Spleen involvement in Hodgkin lymphoma can be assessed by spleen size

Hyperthermia Therapy - New technology could spare many cancer patients from amputation

Immunoaffinity Technology - Tool simultaneously removes multiple proteins from blood serum

Immunology - NF-kappaB plays role in gammaherpesvirus latency

Immunology - Small subset of cells has big role in controlling immunity, study finds

Infectious Disease - IBM to help find genetic links to immune system diseases

Intracranial Chordomas - Radical surgical resection and proton beam radiation therapy yield best results

Laryngeal Cancer - Antioxidant status may be useful to determine the tumor resistance to therapy

Laryngeal Cancer - Tobacco, alcohol appear to account for many cases of laryngeal cancer in women

Leukemia - Cladribine is not worthy of further investigation in adult T-cell leukemia

Leukemia - DDTC-induced cytotoxicity is via oxidative shift in intracellular redox state

Leukemia - Reactive oxygen species are essential mediators in BTS-induced apoptosis

Leukemia and Lymphoma - Childhood ALL may peak in the autumn-winter seasons in Iran

Liver Cancer - Diagnosis, treatment of inferior vena caval invasion by hepatic cancer discussed

Liver Tumors - Hepatectomy using intraoperative ultrasound-guided RF ablation successful

Lung Cancer - CT screening is cost-effective, study shows

Lung Cancer - Cisplatin and etoposide resulted in insufficient long-term disease control

Lung Cancer - Clinical trials are cost-effective alternatives to current standard treatment

Lung Cancer - Combination of RSR13, thoracic radiation may extend survival

Lung Cancer - Connexin 37 gene is not mutated in lung carcinomas 3LL and CMT

Lung Cancer - Enrollment completed in study of Targretin

Lung Cancer - Forty-three percent of patients respond to topotecan treatment in phase II study

Lung Cancer - Genetic alterations of lung cancer in relation to smoking, ethnicity discussed

Lung Cancer - Helical tomotherapy can reduce radiation dose to lung and other normal tissues

Lung Cancer - Melatonin improves the efficacy of chemotherapy and quality of life

Lung Cancer - Nedaplatin and irinotecan were highly effective and well tolerated in NSCLC

Lung Cancer - New Iressa data presented at conference

Lung Cancer - Positive follow-up results reported from trial of Telcyta

Lung Cancer - Pro-gastrin-releasing peptide (ProGRP) can discriminate NSCLC versus SCLC

Lung Cancer - Tumor necrosis therapy receives marketing approval in China

Lung and Breast Cancer - TMSI methylation may play a role in the pathogenesis of lung and breast cancer

Lymphoblastic Leukemia - Patients who didn't have radiation survive as long as general population

Lymphoma - Deregulated expression of BCL6 may allow lymphoma cells to resist chemotherapy

Mantle Cell Lymphoma - PS-341 and BAY 11 induce apoptosis by inhibiting NF-kappa B activation

Medulloblastoma - Reovirus prolongs survival and reduces spinal and leptomeningeal metastases

Melanoma - Betulinic acid can induce programmed cell death in human melanoma cells

Melanoma - National Cancer Institute awards grant for targeted radiotherapy development

Melanoma - Sentinel lymph node may be the only site of regional microscopic nodal disease

Mergers and Acquisitions - Epimmune announces termination of merger agreement

Microhematuria - Researchers clarify diagnosis and treatment in microhematuria

Multiple Myeloma - New drugs appear to overcome drug resistance, bone marrow persistence

Multiple Myeloma - Thalidomide back on the market in Australia by year-end

Mutagenesis - Immunity requires DNA deamination, but the enzyme can act on other DNA

Mutant p53 - Ellipticine can rescue mutant p53 transcription function

Nasal/Paranasal Lymphoma - Local-regional radiation and systemic chemotherapy is recommended

Nasopharyngeal Carcinoma - Epigenetic change in body fluids could be screen for nasopharyngeal carcinoma

Nausea - Researcher working on medical patch to deliver marijuana-like drug

Neoplastic Polyps - DALMs in areas of inflammatory bowel disease should be removed by polypectomy

Neutropenia - Oral antibiotics, early hospital discharge manage low-risk febrile neutropenia

Nicotine Addiction - Teens who notice smokers are more apt to also light up

Oncogenes - Research team reveals molecular key to cell division

Oncogenesis - The role of EGFR in cancer pathogenesis is still not fully understood

Oncology - An amino-terminal portion of the HCVNS3 protein has ties to liver cancer risk

Oncology - Interleukin-1 cytokines and receptors mediate breast cancer progression

Oncology - Lymphangiogenic markers are predictive of colorectal cancer survival

Oncology - Radiofrequency ablation generates 'thermal fixation' of liver cancer

Organ Simulation - Cell culture in human endometrial arrangement may help study metastasis

Osteoid Osteoma - "Beaded" osteoid osteoma may transition from solitary to multicentric tumor

Ovarian Cancer - Experimental immunotherapy in clinical trials

Ovarian Cancer - Flavopiridol enhances radiosensitivity of ovarian carcinoma cells

Ovarian Cancer - Heavier, taller women may have a higher risk of ovarian cancer

Ovarian Cancer - Ovarian carcinoma develops through multiple modes of chromosomal evolution

Pancreatic Cancer - Farnesyltransferase inhibitors are well tolerated

Pancreatic Cancer - Postoperative impact of intraoperative radiation continues to be evaluated

Pancreatic and Colon Cancer - Researchers discuss the role of Smad4 (DPC4) inactivation in human cancer

Pelvic Tumors - Vaginal reconstruction is important to maintain quality of life

Peripheral Edema - Gemcitabine may be associated with potentially serious peripheral edema

Phytotherapy - Green tea extract blocks angiogenesis by halting VEGF receptor expression

Polycythemia Vera - Stem cells from PV patients characterized

Proctocolectomy - A gastric pouch between the ileum and the anus avoids definitive ileostomy

Prostate Cancer - Green tea inhibits angiogenesis and other cancer progression mechanisms

Prostate Cancer - Occupational use of pesticides may be implicated in prostate cancer

Prostate Cancer - Raman spectroscopy shows promise for grading prostatic adenocarcinoma in vitro

Prostate Cancer - Targeting the EGFR function inhibits not only tumor growth but also invasiveness

Prostate Cancer - Three hospitals in the U.K. adopt cryotherapy approach

Proteomics - Clinical applications of proteomics outlined

Proteomics - Models for assessing the role of selenoproteins in health designed

Rejection Control - Tolerance is the ultimate hope for transplant improvement

Renal Cell Carcinoma - PROTEOMEX may identify markers to select patients for immunotherapy

Renal Cell Carcinoma - Polymorphisms of the ERalpha gene may be associated with renal cell cancer

Renal Cell Carcinoma - bHLH-LZ subfamily may be critical in regulating (aberrant) renal cellular growth

Septicemia - Immunocompromised patients' natural flora is main culprit for septicemia

Skin Cancer - Foot melanoma survival rate is just 50%

Solid Tumors - Parents of children with solid tumors have slightly increased incident cancer

Squamous Cell Carcinoma - Researchers identify some novel biomarkers for cutaneous disease

Surgical Advances - Nihilism should not infect science and prevent advancement

Tissue Transglutaminase - Normal and neoplastic lymph nodes have different distribution of the marker

Toxicology - Alcohol-related metabolizing enzymes affect genes that raise liver cancer risk

Transplant Medicine - Carbon monoxide may protect lung transplants from inflammatory damage

Tumor Development - Recombinant expression of 1-8U in human cell lines can block cell proliferation

Tumor Histology - Galectin-3 is expressed by benign and malignant soft tissue tumors

Tumor Imaging - 64-ATSM appears to detect hypoxic but active tumor cell regions in vivo

Tumorigenesis - Researchers decrypt the role of Cripto in tumor growth

Venous Thrombosis - Clearance granted to market removable vena cava filter

Virology - The marmoset can be incorporated into preclinical gene therapy trials

Vision-associated Cancer - Paraneoplastic visual disorder, autoimmune optic neuritis, has cancer risk