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Melanoma

National Cancer Institute awards grant for targeted radiotherapy development

Published in Cancer Weekly, September 9th, 2003

AlphaMed, Inc., announced that it has received a $500,000 2-year STTR phase II grant award from the National Cancer Institute to further develop a targeted radiotherapy for metastatic melanoma.

AlphaMed is collaborating with the University of Missouri in Columbia in this work. The therapy is based on a molecule, labeled with the therapeutic radionuclide lead-212, that is selective to metastatic melanoma cells. Lead-212 decays to bismuth-212, which in turn emits an alpha particle that destroys tumor cells on contact. While melanoma is understood to be relatively radioresistant, alpha particles, with their high-energy deposition, may be effective in metastatic melanoma,...

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