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Prostate Cancer

Allyl isothiocyanate inhibits proliferation of human prostate cancer cells

Published in Cancer Weekly, September 16th, 2003

Allyl isothiocyanate inhibits proliferation of human prostate cancer cells.

According to recent research published in the journal Carcinogenesis, "Dietary isothiocyanates (ITCs) are highly effective in affording protection against chemically induced cancers in laboratory animals.

"In the present study, we demonstrate that allyl isothiocyanate (AITC), a constituent of cruciferous vegetables, significantly inhibits proliferation of cultured PC-3 (androgen-independent) and LNCaP (androgen-dependent) human prostate cancer cells in a dose-dependent manner with an IC50 of similar to 15-17 microM," wrote D. Xiao and colleagues, University...

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