Breast Cancer
Thiamine transporter THTR2 gene expression is downregulated in breast cancer
Published in Cancer Weekly, September 16th, 2003
"The recent molecular identification of two thiamine transporters, SLC19A2 (THTR1) and SLC19A3 (THTR2), has provided the opportunity to study thiamine transporter gene expression in human malignancies," investigators in the United States report.
"We compared RNA levels of both THTR1 and THTR2 in a panel of human breast tumors and corresponding normal tissues. THTR2 RNA levels were down-regulated in breast cancer to 14% of the level found in corresponding normal tissues, while THTR1 levels were unchanged," wrote S.Q. Liu and colleagues, University of Kentucky, Department of...
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Source: Cancer Weekly (2003-09-16)
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