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Lung Cancer

In stage IIIA N2 NSCLC, paclitaxel/carboplatin is an active induction regimen

Published in Cancer Weekly, September 16th, 2003

In stage IIIA N2 NSCLC, paclitaxel/carboplatin is an active induction regimen.

"The aim of this study was to document the activity and toxicity of paclitaxel (Taxol)/carboplatin when used as induction chemotherapy in patients with stage IIIA N2 non-small cell lung cancer (NSCLC) prior to definitive local treatment within a large, ongoing comparative study (EORTC 08941)," investigators in England report.

"Fifty-two eligible, consenting, chemotherapy-naive patients with NSCLC, median age of 60 years, stage IIIA N2 disease and the ability to tolerate a pneumonectomy, received paclitaxel 200 mg/m2 as a 3-h infusion followed by carboplatin at...

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