Melanoma
Ocular melanoma is not associated with CDKN2A or MC1R
Published in Cancer Weekly, September 23rd, 2003
"Germline variants in the melanocortin 1 receptor gene (MC1R) and the p16 gene (CDKN2A) are associated with an increased risk of cutaneous melanoma," investigators in Australia report.
"The frequency of these germline variants was examined in a population-based, incident series of 62 ocular melanoma cases and ethnicity-matched population controls," wrote C. Vajdic and colleagues, Queensland Institute of Medical Research, Cancer & Cell Biology Division.
"In both cases and controls, 59% of individuals carried at least one MC1R variant and there were no significant differences in...
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Source: Cancer Weekly (2003-09-23)
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