Cancer Weekly

Bladder Cancer - Widespread adoption of laparoscopic cystectomy may increase death rate

Brain Cancer - Antigen targeted in melanoma therapy also prompts response in brain tumor cells

Aging - Findings in yeast may reveal why growing older is the greatest carcinogen in humans

Breast Cancer - Antisense p21 ODN triggers breast cancer cell apoptosis

Cancer Risk Factor - Obesity increases risk of some hormone-dependent tumors

Carcinoma - Nitric oxide synthase plays a role in the angiogenesis of bladder cancer

Retinoblastoma - Survivors face increased risk of a second cancer

Actinic Keratoses - Additional patent granted for 5-FU microsponge formulation

Adrenal Cancer - TRF-1 expression level may have prognostic value in adrenal tumors

Advanced Solid Tumors - Cisplatin, irinotecan, and epirubicin have promising broad antitumor activity

Androgen-Deprivation Therapy - Primary hormone induced meningiomas may result from prostate cancer therapy

Angiology - Vascularized nerve graft can achieve upper arm function after sarcoma resection

Anticancer Drugs - Cancer cell chemosensitivity relates to rate of drug shedding in vesicles

Anticancer Drugs - Colorectal cancer may be treatable with 9-cis-RA, tamoxifen plus ciprofloxacin

Anticancer Drugs - Marine organisms may offer source of anti-cancer drugs

Anticancer Immune Response - Investigation of leukemia spontaneous remission cause may lead to cure

Anticancer Therapy - Thymosin alpha 1 may be an important component of anticancer therapy

Antitumor Target - Phospholipase A₂ expression in tumors may target it for therapy

Apoptosis - Melatonin performs cell death functions related to healthy homeostasis

Autoimmunity - Xenogeneic proteins may lead the way to effective cancer vaccines

Bladder Cancer - Inactivation of KLF4 is one of the frequent steps toward bladder carcinogenesis

Bladder Cancer - Polymerase chain reaction has use in urinary diagnosis of bladder cancer

Bladder Cancer - Researchers discuss threshold values for hematuria in cases of bladder cancer

Bladder Cancer - Review of literature evaluates quality of life aspects of bladder cancer

Bladder Cancer - Usefulness of current bladder cancer tests reviewed

Bone Tumors - After cryosurgery, no bone tumor recurrence or complications were detected

Brain Metastases - Radiotherapy prognosis related to RPA class, extracranial metastases, KPS

Brain Tumors - Metastatic pilocytic astrocytoma may be treatable with imatinib mesylate

Brain Tumors - p73 in neuroblastoma may have oncosupressor, oncogenic properties

Breast Cancer - A relationship between breast complaints and cancer onset does not seem to exist

Breast Cancer - Axillary lymph node dissection results in arm motion impairments

Breast Cancer - BRCA1 gene points way to targeting treatment

Breast Cancer - Brand name announced for ABI-007; national sales director named

Breast Cancer - CARP-1 is a novel regulator of retinoids that diminish cancer

Breast Cancer - Comparison study finds better overall response rate, survival with docetaxel

Breast Cancer - Computer-aided detection for breast cancer hits major access milestone

Breast Cancer - Contrast mammography reveals hard-to-find cancers

Breast Cancer - Exemestane demonstrates high tumor response rate

Breast Cancer - FTI and tamoxifen may increase the antitumor effect of either drug alone

Breast Cancer - First Canadian patient treated with site-specific radiation for breast cancer

Breast Cancer - Letrozole is better tolerated, provides better quality of life than anastrozole

Breast Cancer - Low levels of PPARgamma and PGC-I are associated with poor clinical outcomes

Breast Cancer - New evidence eases some concerns about bone fracture risk with anastrozole

Breast Cancer - New treatment guidelines released

Breast Cancer - Novel taxane analogs could effectively kill MDR1-positive breast cancer cells

Breast Cancer - Simulations are comparable to real microcalcifications on digital mammograms

Breast Cancer - Study shows increased risk for stressed women, but more research is needed

Breast Cancer - Study shows link between children's solid tumors and mothers' cancer risk

Breast Cancer - Trial of new breast imaging device set to begin; NIH buys molecular imager

Breast Cancer - Vitamin A intake may be related to a reduced risk of breast cancer among smokers

Breast Cancer - Women who use antihistamines are not at higher risk for developing breast cancer

Breast Cancer - Women with mutated BRCA 1 or 2 should avoid repeated x-ray use

Breast Cancer - Younger U.K. women prefer hormonal treatment for breast cancer

Breast Cancer Immunology - CD1a+ dendritic cell density may be linked to higher breast cancer survival

Breast and Ovarian Cancer - The roles of BRCA1 alternative splicing are emerging

Cancer Control - Researchers call for international forum for cancer control research advancement

Cancer Epidemiology - Mortality rates were higher than expected for lung cancer overall

Cancer Fatigue - Gaps still remain in assessment, management of cancer-related fatigue in adults

Cancer Mortality - Cancer survival gap between Western, Eastern Europe "substantial and increasing"

Cancer Pain - Better pain control for ambulatory cancer patients is needed

Cancer Pain - End-of-life cancer pain can be prevented

Cancer Prevention - COX inhibitors have potential in cancer prevention and therapy

Cancer Research - Hedgehog pathway implicated in human pancreatic carcinoma and other cancers

Cancer Risk - Physical exercise reduces risk of estrogen-dependent cancers and colon cancer

Cancer Risk Factor - Exercise intensity affects risks of cancer

Cancer Screening - DETECT Study: HMOs should try to improve older women's testing compliance

Cancer Screening - Differences in cancer rates vary by ethnicity even within similar income groups

Cancer Therapy - COX-2 inhibitors may be used as radiosensitizing agents for cancer therapy

Cancer Therapy - Canadian company gets patents protecting cancer and infectious disease programs

Cancer Therapy - FDA approves Ganite for treatment of cancer-related hypercalcemia

Cancer Therapy - FDA grants fast track designation for Advexin

Cancer Therapy - Third clinical trial with GTI-2040 to begin in cooperation with NCI

Cancer Therapy - Thrombogenic fusion proteins diminish the vascularity of tumors

Cancer Vaccine - Carbohydrate-specific antibodies make potential cancer vaccine for human use

Cancer Vaccine - Glycosylamino acids with tumor-associated carbohydrate antigens synthesized

Cancer-related Weight Loss - Nutritional product reverses weight loss in advanced cancer patients

Cell Signaling - Molecular mechanism underlying tumor selectivity of Hsp90 inhibitors identified

Cervical Cancer - A single vaccine could benefit most women

Cervical Cancer - New U.S. global AIDS law will undermine condom use, not help women, paper says

Cervical Cancer - New guidelines published for HPV DNA testing in cervical cancer screening

Chemotherapy - Davanat increases anticancer efficacy of 5-fluorouracil

Chemotherapy - New developments in drug delivery have implications for cancer care

Childhood Cancer - Chemotherapy decreases epiphyseal strength and increases bone fracture risk

Colon Cancer - Clusterin may be a biomarker in murine and human intestinal neoplasia

Colon Cancer - Dysregulated RNA-binding of TIA-1 promotes COX-2 expression in neoplasia

Colon Cancer - Legislation provides health coverage for colorectal screenings

Colon Cancer - Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cells

Colon Cancer - Nordic collaboration gives new insights into adjuvant chemotherapy

Colon Cancer - Practice parameters established to treat dominantly inherited colorectal cancer

Colorectal Cancer - Aminosalicylates may have chemopreventative value in IBD

Colorectal Cancer - FDA grants priority review to Eloxatin

Colorectal Cancer - Vioxx may be a chemopreventive in humans at risk for colorectal neoplasia

Complementary and Alternative Medicine - A trained visitor dog could be viewed as part of cancer patients' therapy

Cutaneous Melanoma - Less extensive diagnostic procedures are sufficient in primary tumor stages

Dendritic Cell Vaccine - Dendritic cells respond to antigens through heat shock protein receptor

Diagnostic Imaging - Intermittent-bolus contrast imaging is valuable for studying tumor perfusion

Diagnostics - Molecular diagnostic test manufacturer earns ISO 9001:2000 certification

Diagnostics and Therapeutics - Pharmaceutical company signs agreement for SF-25 oncology program

Diet and Nutrition - Maternal folic acid intake linked to decrease in deadly childhood cancer

Drug Development - Company wins NIST funding for a D-amino acid drug development platform

Drug Development - Surface cavities of alpha(1)-antitrypsin could be targeted for liver therapy

Embryogenesis - Mechanical stress alters developmental gene expression

Endocrinology - An autocrine loop controls angiogenic growth factors in pancreatic cancer

Enzymology - COX-2 inhibition may be of use for controlling epithelial malignancy

Epithelial Differentiation - CD44v6 is involved in oral epithelial differentiation but not cancer

Epstein Barr Virus - Targeting therapy to virus is best way to selectively eliminate EBV cancers

Esophageal Cancer - Combination use of intracavitary brachytherapy refines treatment outcome

Esophageal Cancer - Irinotecan and docetaxel shows some activity in extensively pretreated patients

Extremity Sarcomas - Complex reconstruction helps in the management of extremity sarcomas

Finance - $30M financing closed by oncology company

Finance - Cancer test maker closes private offering, updates warrant exercises