Carcinoma

Nitric oxide synthase plays a role in the angiogenesis of bladder cancer

Published in Cancer Weekly, October 14th, 2003

Nitric oxide synthase plays a role in the angiogenesis of bladder cancer.

"Nitric oxide (NO) is synthesized by the enzyme family of nitric oxide synthases (NOS) and plays an important role in tumor growth and angiogenesis. The expression of two of the NOS isoforms, the endothelial and inducible isoforms (eNOS and iNOS, respectively), were evaluated in bladder tissue from patients with transitional cell carcinoma (TCC). The specimens were procured from 58 patients with TCC and 14 cases of normal bladder mucosa were used as a control group," scientists in the Peoples Republic of China report.

"NOS immunohistochemistry was performed and microvessal...

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Source: Cancer Weekly (2003-10-14)

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