Hematology

Platelet proteinase-activated receptors play a significant role in tumor growth

Published in Cancer Weekly, October 28th, 2003

Platelet proteinase-activated receptors play a significant role in tumor growth.

"With respect to the role of proteinase-activated receptors (PARs), few cells have been as thoroughly studied as the platelet. PARs appear to act as the key receptors mediating the pro-aggregatory and pro-secretory effects of thrombin, but there is considerable variation from species to species in terms of which PARs are involved in these processes. In addition to contributing to hemostasis, platelets are increasingly being viewed as important contributors to healing and to tumor growth," investigators in Canada report.

"This can be attributed to the many pro- and...

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Source: Cancer Weekly (2003-10-28)

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