Childhood Tumors

Clinical, cellular pharmacology in relation to childhood solid tumors reviewed

Published in Cancer Weekly, October 28th, 2003

Clinical and cellular pharmacology in relation to solid tumors of childhood are reviewed.

According to recent research published in the journal Cancer Treatment Reviews, "Our understanding of the clinical and cellular pharmacology of drugs commonly used in the treatment of childhood cancer have increased greatly over the past 2 decades.

"However, with the exception of childhood acute lymphoblastic leukemia (ALL), our current knowledge of factors such as interpatient pharmacokinetic variability and cellular determinants of chemosensitivity has not been utilized in the design of integrated clinical studies," wrote E.J. Estlin and colleagues,...

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Source: Cancer Weekly (2003-10-28)

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