Cancer Weekly

Leukemia - Comprehensive gene profiles hold promise for improving outcomes

Stem-Cell Research - Researchers grow breast cancer tissue from transplanted mammary stem cells

Breast Cancer - Herpes simplex virus-1 treatment of primary tumors reduces metastatic cancer

Cancer Therapy - BOLD-contrast MRI monitors the vascular characteristics of tumors in real-time

Colorectal Cancer - Naturally occurring lignans useful in colorectal tumor therapy, chemoprevention

Oncology - Several risk factors are associated with hepatocellular carcinoma metastasis

AIDS Co-infections - Data: Hepsera associated with sustained reductions in hepatitis B virus

Acute Myeloid Leukemia - High expression levels of cyclin A2 and A1 are associated with good prognosis

Anticancer Agents - Mode of action of docetaxel described

Anticancer Agents - Tea and its components have chemo-protective effects

Antisense Technology - Bcl-x(L) antisense oligonucleotides sensitize colon cancer cells to radiation

Antitumor Therapy - Poorly soluble antitumor drugs can be delivered by PEG-PE-antibody micelles

Awards - NewsRx wins 2003 eHealthcare Leadership awards

Bladder Cancer - The HOX gene network, especially locus C, may be involved in bladder cancer

Bladder Cancer - Tocosol Paclitaxel receives expedited review for bladder cancer indication

Blood Pressure - Daily serving of strawberries can decrease systolic blood pressure

Brachytherapy - FDA 510(K) clearance of the COMFORT catheter system announced

Breast Cancer - Ala-9Val MnSOD polymorphism has no association in development of breast cancer

Breast Cancer - Breast cancer outreach model using professional, volunteer staffing studied

Breast Cancer - BreastCare/BreastAlert Differential Temperature Sensor ordered in Brazil

Breast Cancer - Collaborative agreement set to develop new breast cancer vaccine

Breast Cancer - Disease can be reversed in laboratory mice, scientists report

Breast Cancer - Germline BRCA1 mutations appear to be associated with breast cancer phenotype

Breast Cancer - New devices provide more accurate diagnosis

Breast Cancer - New test could predict response to tamoxifen and anastrozole

Breast Cancer - No clear winner among ways to encourage mammograms

Breast Cancer - Study verifies Id-1 gene as target for cancer gene therapy

Breast Cancer - What factors differentiates 'missed' from 'reported' breast cancers are analyzed

Breast Cancer - Young women who choose lumpectomies need indefinite follow-up, study says

Breast Cancer - c-erbB-2 adds no prognostic information when PAI-1 are candidates

Cancer Care - Health care communication model involving patients, doctors, family presented

Cancer Cell Biology - New pathway found to enhance cancer treatment

Cancer Cells - Research shows that PUMA gene is key in ridding body of weakened cells

Cancer Communication - Findings on physician-older patient communication about cancer can improve care

Cancer Detection - Alliance targets development of molecular fingerprinting technology

Cancer Education - Mediated consumer-provider communication in cancer care is presented

Cancer Immunotherapy - Company moves towards clinical trials with TAP cancer vaccine

Cancer Mechanics - Hypoxia stimulates melanoma progression and invasion

Cancer Medication - Concordance can help to identify gaps and opportunities for research

Cancer Metastasis - Flt-1 plays an unprecedented role in the survival of cancer cells

Cancer Prevention - Role of tea in cancer prevention is examined

Cancer Research - Communication, consumer decision making about cancer clinical trials evaluated

Cancer Screening - LungAlert test added to international lung cancer screening study

Cancer Therapy - Canadian company reports progress on selective HDAC inhibitor chemistries

Cancer Therapy - Endoglin is a strong therapeutic target for angiogenesis inhibition

Cancer Therapy - PTEN gene delivery inhibits human colorectal cancer growth

Cancer Treatment - Biotech company and cancer institute to explore cancer treatment's potential

Cancer Vaccine - Converting tumors to Ii protein-negative phenotype causes tumor shrinkage

Cardiac Masses - Magnetic resonance imaging of cardiac and paracardiac masses may be useful

Cervical Cancer - Array-based technologies may usher in a new era in diagnosis

Cervical Cancer - The role of topotecan in the treatment of advanced cervical cancer reviewed

Cervical Cancer - Update on current concepts of atypical squamous cells is presented

Cervical Cancer - X chromosome inactivation in cervical cancer patients is evaluated

Chemotherapy - Cells may actively reorganize environment to maximize survival

Chronic Myelogenous Leukemia - Troxacitabine can resolve a portion of imatinib mesylate-resistant leukemias

Collaborations - Biotech service company and research center enter collaborative agreement

Collaborations - Medarex enters antibody deal

Collaborations - Successful research partnership concludes

Colon Cancer - Cdx1 inhibits the proliferation of human colon cancer cells

Colon Cancer - Direct link found between chronic inflammation, cancer

Colorectal Cancer - Cumulated genetic alterations in colorectal cancer are assessed

Colorectal Cancer - Medicare will cover screening immunoassay fecal-occult blood tests

Colorectal Cancer - Microsatellite-unstable CRC characterized by novel patterns of gene expression

Colorectal Cancer - The epidemiology of tea consumption and colorectal cancer incidence reviewed

Complementary and Alternative Medicine - Flavonoids alter angiogenic mechanisms by controlling specific signals

Diet and Nutrition - In vivo alpha-tocopherol effects offset by reduced gamma- and delta-tocopherol levels

Drug Abuse - Alcohol use increases risk of hormonally sensitive breast cancers

Drug Development - TZT-1027 blocks lung cancer vascular endothelial growth factor expression

Drug Development - Therapy that could strike down VEGFR-2 would be a potent anticancer tool

Endometrial Cancer - Treatment options for endometrial cancer are reviewed

Esophageal Cancer - Stent is effective treatment for perforation of obstructing esophageal cancer

Finance - CAMPATH momentum leads to improved 2003 sales guidance

Finance - Cancer vaccine maker reports loss of $0.35 per share

Finance - Drug delivery company reports $0 loss per share

Finance - Ganite maker reports reaching major corporate milestones in third quarter

Finance - Hectorol maker reports 50% increase in sales

Finance - IMPAC reports record earnings, sales, and backlog for fiscal year 2003

Finance - Immunotherapy company announces IPO on Nasdaq

Gastric Cancers - Cytoplasmic TFF2 is a marker of gastric tumor metastasis

Gastroenterology - Influential genes control gastric cancer growth, angiogenesis, and metastasis

Gene Tracking - The in silico functional gene screening method identifies proangiogenic genes

Genetic Engineering - Frustrated cancer researchers: Who owns our mice?

Genomics - Chronic oxidative stress may disrupt the genomic integrity of cells

Genomics - Common genetic evolutionary pathways in FAP tumors are evaluated

Genomics - MYC and the WNT pathway may have a role in maintaining susceptibility to TRAIL

Gynecology - ETS-1 may be a biomarker for the angiogenesis of ovarian cancer

Head and Neck Cancer - PUMA does not appear to be target of inactivation in head, neck tumorigenesis