Ovarian Cancer

Topotecan use may offer opportunities for improving management of ovarian cancer

Published in Cancer Weekly, November 25th, 2003

Topotecan use may offer opportunities for improving management of ovarian cancer.

"Topotecan is an established therapy for the treatment of recurrent ovarian cancer and has demonstrated significant antitumor activity in both platinum-sensitive and platinum-resistant patient populations," scientists writing in the journal Gynecologic Oncology report.

"The main toxicity associated with topotecan when used in the standard 5-day dosing schedule is myelosuppression, which is generally predictable, reversible, noncumulative, and manageable. Comparative trials have shown that topotecan is as effective as paclitaxel and pegylated liposomal doxorubicin...

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Source: Cancer Weekly (2003-11-25)

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