Gene Tracking
The in silico functional gene screening method identifies proangiogenic genes
Published in Cancer Weekly, November 25th, 2003
"Angiogenesis, the formation of new blood vessels out of pre-existing capillaries, occurs in a variety of pathophysiological conditions, and is regulated by a balance of angiogenic activators and inhibitors. To identify novel angiogenic factors, we developed a gene screening method by combining the prediction analysis of transcription factor (TF) binding site and the chromosomal localization analysis," researchers in South Korea report.
"First, we analyzed the promoter sequences from known angiogenesis-related factors using the MATINSPECTOR program in TRANSFAC database....
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Source: Cancer Weekly (2003-11-25)
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