Susan Hasty, Publisher
Table of Contents . . . December 2nd, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cancer Weekly | Other Publications
Antitumor Drugs - Two CD95 tumor classes with different sensitivities to antitumor drugs
Lung Cancer - Adenoviral overexpression coupled with lab assays can uncover gene profiles
Brain Cancer Therapy - Ruta 6 induces selective apoptosis in glioma cells
Immunology - Transparent fish provide window on blood formation and marrow transplantation
Lung Cancer - Safety and efficacy of low-dose docetaxelin advanced non-small cell lung cancer
Skin Cancer - Nonmelanoma cancer associated with other cancers
Acute Myeloid Leukemia - Farnesyltransferase inhibitors in AML and myelodysplastic syndromes
Antifungal Therapy - Improved diagnosis of fungal infections no longer requires preventive therapy
Atrial Myxoma - Myxoma of the right atrium could be due to fusion of giant cells
Awards - Moshe Oren named winner of NIH MERIT Award
Bile Duct Stones - Management of common bile duct stones: The state of the art in 2000
Blood Pressure and Cancer - Blood pressure and site-specific cancer mortality
Blood Substitute - Perfluorocarbon-based blood substitute undergoes phase I clinical trial
Breast Cancer - 14-3-3 Sigma positively regulates p53 and suppresses tumor growth
Breast Cancer - Bone sialoprotein overexpression fosters cancer cell metastasis in study mice
Breast Cancer - Breast cancer detection system receives marketing approval from FDA
Breast Cancer - Comparative transductions of breast cancer cells by three DNA viruses
Breast Cancer - Coping and posttraumatic growth in women with early-stage breast cancer
Breast Cancer - Danish researchers use image data software to help breast cancer research
Breast Cancer - Diagnosis of axillary nodal metastases by ultrasound-guided core biopsy
Breast Cancer - EZH2 is a marker of aggressive breast cancer
Breast Cancer - FDA gives approval for phase III registrational trial for breast cancer drug
Breast Cancer - Flavonoid intake and breast cancer risk: a case-control study in Greece
Breast Cancer - Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 breast cancer
Breast Cancer - PET imaging still questionable as means of predicting chemotherapy response
Breast Cancer - Surgical treatment for elderly breast cancer patients over age 70
Breast Cancer - The LeJour vertical mammoplasty pattern for skin-sparing mastectomy
Breast Cancer - iCAD, Inc. to distribute iQ Tabletop CAD System
Breast Cancer Screening - Cancer registry useful for Florida breast cancer early detection program
Breast Implant - Canadian study confirms women with implants require more medical care
Breast Implants - Causes of death among Finnish women with cosmetic breast implants, 1971-2001
Breast Reconstruction - Improving recipient vessel exposure during microvascular breast reconstruction
Cancer Caregivers - Measuring the burden, needs, and quality of life of informal caregivers
Cancer Cells - Choline phospholipid metabolism: A target in cancer cells?
Cancer Metastasis - Drosophila genetics can be a screening model for metastasis
Cancer Metastasis - Gene therapy containing p53 combines with CDDP to arrest liver tumor growth
Cancer Nursing - Onward in my journey - preparing nurses for a new age of cancer care
Cancer Proteomics - VEGF-C might act as a switch for tumor metastasis
Cancer Risk Factors - Hepatitis B virus genes promote liver cancer in chronic hepatitis C patients
Cancer Therapy - COX-2, cAMP and protein kinase A traverse integrins to regulate angiogenesis
Cancer Therapy - Genetic loci mark host response to angiogenic control
Cancer Therapy - Real-time imaging depicts how TRAIL can treat tumors
Cancer Therapy - Risk of second malignancy high after HDT and stem-cell autotransplantation
Cancer Treatment - Radiofrequency ablation being used to treat cancerous tumors
Cancer Vaccine - Tumoral immune resistance based on tryptophan degradation by enzyme
Cardiac Toxicity - Free radicals mediate cardiac toxicity induced by adriamycin
Cardiomyopathy - Cardiac patient with complications delivers healthy baby
Cervical Cancer - KCl cotransport is an important modulator of cervical cancer growth and invasion
Cervical Cancer - National coverage initiated for DNAwithPap test
Cervical Cancer - The development of high-dose-rate brachytherapy for cervical cancer in Japan
Chemotherapeutic Agents - Acid pH affects the distribution of chemotherapeutic agents in vitro
Childhood Cancer - Vitamin K is not associated with the development of childhood cancer
Clinical Trial - Challenges of recruitment and retention in multisite clinical research
Collaborations - Alliance with the Cleveland Clinic uses imaging system in cancer research
Collaborations - Miikana Therapeutics inks strategic alliance for antibody development
Colon Cancer - High expression of CD55 by colorectal cancers is predictive of low survival
Colon Cancer - Modified de Gramont with oxaliplatin in treatment of advanced colorectal cancer
Colon Cancer - Motility of colon cancer cells: modulation by CD44 isoform expression
Colon Cancer - Probiotic bacteria may inhibit colon cancer
Colorectal Cancer - 2003 survey shows limited awareness of cancer prevalence
Colorectal Cancer - Multivitamin use and colorectal cancer incidence in a U.S. cohort
Colorectal Cancer - NSAIDs inhibit colorectal neoplasia
Colorectal Cancer - Rates of colon and rectal cancers are increasing in young adults
Cytology Fixation Method - Cytology smears retain best antigen reactivity if directly fixed in 95% ethanol
DNA Damage - Mechanism of apoptotic resistance of human osteosarcoma cell line elucidated
Diagnostics - Imaging company inks agreement with the Rumbaugh-Goodwin Institute
Diagnostics - Peripheral blood mononuclear cells express different genes in kidney cancer
Diagnostics - Tumor oxygen use, hypoxia, can be observed by MRI with FREDOM
Drug Abuse - Inhalant nitrite alters hepatic angiogenic gene expression in mice
Drug Development - HIF-1 may be target for future cancer and heart disease drugs
Drug Discovery - Research agreement supports computer-assisted molecular design of medicines
End-of-Life Care - Assisted dying and end-of-life symptom management
Finance - Biopharma company announces third quarter 2003 financial results
Finance - Diagnostics company reports third quarter results; bladder cancer test revenues up 87%
Finance - Drug delivery company announces third quarter 2003 results
Finance - Genomics company reports loss of $0.35 per share; provides pipeline update
Finance - Immunotherapeutics company reports $7.4M in revenue
Finance - Oncology company reports loss of $0.19 per share
Finance - Pharmaceutical company reports record third quarter revenues; total revenues up 24%
Gastric Cancer - Broad potential reported for R1549 highlighted by favorable tolerability profile
Gastric Cancer - Detection of p53 mutations in precancerous gastric tissue
Gene Delivery - Rearranged cell activity enhances how RAD50 gene therapy affects angiogenesis
Gene Transfer - SMAD4 gene therapy halts the invasiveness of pancreatic adenocarcinoma cells
Genetic Engineering - ONYX-015 augments radiotherapy directed against thyroid cancer cells
Genetic Mutations - Genetic and epigenetic alterations as hallmarks of the intricate road to cancer
Genomics - Genomic instability and cancer
Genomics and Genetics - P2X7 receptor gene polymorphism does not affect survival in leukemia
Gynecology - PTEN overexpression squashes the migration of ovarian cancer cells
Head and Neck Cancer - Physiological and molecular genetic alterations in head and neck cancer
Hematologic Malignanc - Bone marrow evaluation in pediatric patients
Hematologic Malignancies - Chromosomal translocations in human malignant hematopoiesis
Hematologic Malignancies - Epoetin alfa therapy for patients with hematologic malignancies and mild anemia
Hematopoietic Cell Transplant - Keeping DC immaturity may induce tolerance for transplant of hematopoietic cells
Hepatic Cancer - The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis
Immunology - Antisense blockade of Stat5a/b promotes the apoptosis of lymphoid cells
Information Technology - Custom lab system designed for breast cancer project
Inoperable Liver Cancer - Liver cirrhosis with inoperable liver cancer treated by intratumor ethanol, IL-2
Keratinocyte Carcinoma - Keratinocyte carcinoma is the most common cancer in the United States
Kidney Cancer - Reduced-intensity stem-cell transplantation may slow RCC progression
Leukemia - Chromosomal abnormalities in secondary myelodysplastic syndromes and leukemias
Leukemia - Cytogenetic findings in adult de novo acute myeloid leukemia
Leukemia - DNA microarray stem cell analysis can differentiate de novo and MDS-related AML
Leukemia Therapy - Cyclosporine and IFN-gamma treatment after auto-SCT improves outcome
Leukemia Therapy - Cytoreduction may be needed for curative SCT in CML patients
Leukemia Therapy - Imatinib treatment can improve SCT outcome in Ph+ ALL patients
Leukemia Therapy - Persistent iron overload common in long-term AML survivors after stem-cell autografting
Lung Cancer - Bronchoscopic insertion of Gianturco stents for the palliation of lung cancer
Lung Cancer - Chymase positivity may predict outcomes in patients with localized lung cancer
Lung Cancer - Gemcitabine with cisplatin or epirubicin in advanced non-small-cell lung cancer
Lung Cancer - Group highlights what women don't know about their top cancer killer
Lung Cancer - Menthol cigarettes and risk of lung cancer
Lung Cancer - Proteomic approaches to biomarker discovery in lung cancers by SELDI technology
Lung Cancer - Tumor dimension and prognosis in surgically treated lung cancer
Lung Cancer - Tumor size predicts survival in patients with lung cancer
Lung Cancer - Weekly carboplatin and paclitaxel in elderly non-small-cell lung cancer patients
Lung Cancer Mutation - Lung tumor suppressor TSLC1 binds MPP3; mutation in TSLC1 disrupts cell adhesion
Lymphoma - Waldeyer ring lymphomas: Treatment results and prognostic factors
Lymphoma Therapy - Involved field radiation therapy raises TRM risk in stem-cell transplant recipients
Lymphoma and Myeloma - Cytogenetic abnormalities in malignant lymphoma and multiple myeloma
Maesa Lanceolata Benzoquinones - Antitumor, antioxidant effects seen in vitro for some alkylated benzoquinones
Malaria Therapy - Oxidative stress underlies antitumor activity of artesunate
Malignant Melanoma - Company files for European approval to market Ceplene
Mediastinal Tumors - Surgical treatment for giant solid tumors of the mediastinum
Mesothelioma - Blood marker for diagnosis shows early promise
Metastasis - Tumor growth follows same curve as animal growth
Multiple Myeloma - MIP-1 alpha levels correlate with survival in multiple myeloma patients
Mutagenesis - Thrombospondin 1 restoration by low-dose doxycycline may control angiogenesis
Myelodysplastic Syndrome - The role of erythropoietin in the anemia of myelodysplastic syndrome
Non-Hodgkin Lymphoma - Data release from phase III ECOG 4494 study of Rituxan
Occupational Exposure - Aromatic hydrocarbon-DNA adducts are higher in leukocytes of rickshaw drivers
Oncology - Enzyme upregulation in the T cells of mammary tumor bearers points to invasion
Oncology - Reactive oxygen species exacerbate the effects of hepatitis B virus X protein
Oncology - The angiostatic properties of STI-571 may be valuable therapy for many disorders
Oncology Trials - Clinical trials in pediatric cancer: Parental perspectives on informed consent
Osteosarcoma - p53 mutations in osteosarcomas correlate with high levels of genomic instability
Ovarian Cancer - A phase II trial of bryostatin-I in recurrent epithelial ovarian carcinoma
Ovarian Cancer - Granulosa cell tumor of the ovary - Retrospective analysis of 45 cases
Ovarian Cancer - Liposomal doxorubicin and gemcitabine in the salvage treatment of ovarian cancer
Ovarian Cancer - Reproductive factors and epithelial ovarian cancer risk by histologic type
Pancreatic Cancer - BRAF and K-ras gene mutations in human pancreatic cancers
Patents - Court upholds stem-cell patents
Personnel - Diagnostic testing company promotes Paul Touhey
Personnel - Eric von Hofe named VP of technology development
Personnel - VP treasury, financial operations named at oncology drug company
Phytotherapy - Saikosaponins from Bupleurum exhibit antiviral and anticancer properties
Pituitary Tumors - The Kruppel-like transcription factor 6 gene in sporadic pituitary tumors
Prostate Cancer - Functional results of various surgical techniques for radical prostatectomy
Prostate Cancer - Genetic mapping of allelic loss on chromosome 6q in prostate carcinoma
Prostate Cancer - Improving quality of life in men with prostate cancer
Prostate Cancer - Indications for and results of radical prostatectomy
Prostate Cancer - No association of germline alteration of MSR1 with prostate cancer risk
Prostate Cancer - Transrectal ultrasound-guided punch biopsies of the prostate
Proteomics - Thyroid stimulating hormone regulates VEGF from alternative tissues
Pulmonary Cancer - Ultrasonographic localization of occult pulmonary nodules during VATS
Radiation Therapy - Report from the SWOG Radiation Oncology Committee 2003
Rectal Cancer - Endocavitary radiation therapy for rectal adenocarcinoma - 10-year results
Rectal Cancer - Rectal carcinoma in Egyptian patients less than 40 years of age
Reimbursement - Medicare to cover annual InSure testing for colorectal cancer screening
Renal Cancer - Surgical treatment of pulmonary metastases from renal cancer
Renal Tumors - Molecular subclassification of renal tumors and discovery of diagnostic markers
Sarcoma - PET with fluorine-18-deoxyglucose in detecting recurrent and metastatic sarcoma
Skin Cancer - New and emerging topical approaches for actinic keratoses reported
Small Cell Lung Cancer - Inactivation of Trp53 and Rb1 in lung endothelial cells creates SCLC in mice
Squamous Cell Carcinoma - First commercially licensed gene therapy drug approved for production
Stem-Cell Transplantation - Data on AMD3100 to be presented at ASH
Stem-Cell Transplantation - Infliximab raises post-SCT risk of non-Candida invasive fungal infections
Stem-Cell Transplantation - Post-PBSCT leukocyte and cytokine profiles determined
Substance Abuse - School-based prevention program reduces smoking and alcohol use in children
T-Cell Anergy - Chronic exposure to antigen induces IFNgamma-dependent TCR downregulation
Telemedicine - Memorial Sloan-Kettering signs with telemedicine company
Terminal Cancer - Effect of nebulized furosemide in terminally ill cancer patients with dyspnea
Thyroid Cancer - Antitumor compound to be tested in newly diagnosed cancer patients
Thyroid Tumor Diagnostics - Galectin-3 is expressed in higher amount only in papillary thyroid carcinomas
Tobacco Use - Low monoamine oxidase B in peripheral organs in smokers
Tumor Hypoxia - Hypoxia-inducible transcription factors influence cell types differentially
Tumor Suppression - The quest for a tumor suppressor gene phenotype
UV Exposure - Enzymes for melanin production in Koreans increase for a week after UV exposure
Ultraviolet Exposure - Polymorphisms in DNA repair genes may be linked to immunosuppression, cancer
Ultraviolet Irradiation - UVB, UVC irradiation damage is detectable with antiserum in histology or ELISA
Vector Development - Fusion gene products facilitate the study of enzyme-mediated gene therapy
Venous Thromboembolism - Epidemiology and management of venous thromboembolism in patients with cancer
Ventilator Withdrawal - Ventilator withdrawal: Procedures and outcomes
Women's Health - Dietary folate can counteract effects of alcohol on chronic disease risk
Women's Health - Mastopathy occurs as result of diabetes
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