Susan Hasty, Publisher
Table of Contents . . . December 23rd, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cancer Weekly | Other Publications
Larynx Cancer - New standard for voice-saving care of patients introduced
Multiple Myeloma - Origin of bone marrow cancer found in rare stem cell
Colorectal Cancer - Calcium and vitamin D collaborate to reduce risk
Gene Therapy - CD46 acts as cellular receptor for group B adenoviruses
Prostate Cancer - Gene therapy and radiation combination shows promise in prostate cancer study
Antifungal Therapy - Pediatric patients may benefit from voriconazole for invasive aspergillosis
Antitumor Radiotherapy - Leaky radiohalogen labels used in targeting tumors can be modified for retention
Brain Disease - Water diffusion in brain disease and ischemia can be detected by diffusion MRI
Breast Cancer - Better prognosis for HRT users more likely due to frequent screening
Breast Cancer - Breast tumors can be organized into subclasses based on markers; may aid therapy
Breast Cancer - Breast-conserving therapy offers good outcome if criteria are met
Breast Cancer - CAD software improves breast ultrasound, digital mammograms
Breast Cancer - CYPRED catalyzes doxorubicin in liver; not active against breast cancer cells
Breast Cancer - Clinical images of blood flow in breast may facilitate cancer diagnosis
Breast Cancer - Comparison study finds no survival difference between fulvestrant, anastrozole
Breast Cancer - Drug that eases tamoxifen side effect may also hinder its effectiveness
Breast Cancer - EGFR status linked to poor survival in patients with advanced disease
Breast Cancer - FDA clears new method for managing non-cancerous breast lumps
Breast Cancer - New genetic test may help patients make chemotherapy decision
Breast Cancer - New scanner can detect early signs of disease
Breast Cancer - Outpatient procedure shrinks benign breast lumps
Breast Cancer - Pennsylvania Breast Cancer Coalition to receive research grant
Breast Cancer - Scientists find better way to predict disease outcome following surgery
Breast Cancer - Study looks at etiological role of early exposure to household chemicals
Breast Cancer - Study shows improved survival rates, time to disease progression with docetaxel
Breast Cancer - Surgery without radiation inadequate for DCIS, study shows
Breast Cancer - Tumor vaccine to begin clinical trials
Business & Finance - Digene added to NASDAQ Biotech index
Cancer Detection - Detection companies announce expanded partnership
Cancer Detection - Detection companies join to expand computer-aided detection
Cancer Epidemiology - The viral etiology of hepatocellular carcinoma in Greece has changed
Cancer Genomics - The HC gp-39 gene is a biomarker for progression in astrocytic glioma
Cancer Imaging - Future cancer imaging methods can use mammography as a learning base
Cancer Prevention - Angiogenesis is one of several activities targeted by vitamin D and its analogs
Cancer Proteomics - Oncostatin-M causes astroglioma cells to produce angiogenic growth factor
Cancer Therapy - Advexin therapy to be combined with surgery in phase II trial
Cancer Therapy - CV-IBS provides early warning of doxorubicin-induced heart damage
Cancer Therapy - Company announces phase I/II trial development of MDX-214
Cancer Therapy - Company reports on monoclonal antibody therapeutics advancements
Cancer Therapy - Endothelial progenitor cells carry gene therapy to solid tumors
Cancer Therapy - Technique kills cancerous cells, leaves healthy cells intact
Cancer Therapy - Thrombospondin 1 augments low-dose metronomic chemotherapy
Cancer Vaccine - Tumor antigen plus GM-CSF ends immunological ignorance to tumor antigen
Cervical Cancer - Cervical cancer prevention and treatment reviewed
Cervical Cancer - HPV testing could be future strategy for primary screening
Cervical Cancer - HPVDNAChip detects multiple human papillomavirus strains in cancer specimens
Clinical Trials - Company summarizes irofulven clinical data
Colon Cancer - Company reports on bispecific antibody technology
Colon Cancer - Human colorectal cancer treated with 5-FU, anticancer drugs, by gene profiling
Colon Cancer - License agreement made for computer-aided detection tools in colonoscopy
Colon Cancer Screening - 3-D virtual colonoscopy is more sensitive than conventional procedure
Colorectal Cancer - Erbitux cancer drug approved and available in Switzerland
Colorectal Cancer - NDS filed with Health Canada for Erbitux
Colorectal Cancer - Study examines risk factors associated with colorectal cancer
DNA Damage - DNA damage plays role in genetic predisposition to arsenic cytotoxicity
Data Management - Encoded CAP Cancer Checklists help pathologists report common forms of disease
Dermatology - Pulsed dye laser treatment of glomangiomyoma results in complete pain relief
Drug Development - Derivatives of a potent anti-herpes agent improve the efficacy of gene therapy
Drug Development - Microtubule inhibitors given as anticancer therapy are improving
Drug Development - New sarcodictyin/eleutherobin analogs have less cytotoxicity than paclitaxel
Endocrinology - 17 Beta-estradiol regulates cytokine release from macrophages
Endocrinology - Small-molecule inhibitors override the angiogenic potential of thyroid cancer
Ethnic Variation - The CD1D gene has haplotypes that differ in prevalence between ethnic groups
Finance - Cancer diagnostics company closes $4 million bridge financing
Finance - Surgical product company completes equity placement
Gastric Cancer - Fecal samples from gastric cancer, even hyperplasia tend to be gp87 positive
Gastric Carcinoma - Gastric cancer with high MIP-1 beta expression correlate with metastasis risk
Genomics - New publication of research into therapeutic treatments for cancer
Gynecology - Patients with borderline nuclear change in cervical smears warrant follow-up
Head and Neck Cancers - Photodynamic therapy used to treat cancer of the head and neck
Helicobacter Pylori - Purified H. pylori CagA, HspB proteins can induce gastric cell division
Hematologic Cancer - HTLV-1 Tax oncoprotein inhibits hematopoiesis
Hepatocellular Carcinoma - Lonidamine increases tamoxifen, other antiproliferative activity on HCC
Hodgkin Disease - Some patients develop heart problems years after radiation treatment
Immunoliposomes - PEG-modified liposomal doxorubicin with GAH targets GI cancer cells with antigen
Leukemia - Allelic evolution of C/EBP-alpha mutations occur in myeloid leukemia
Leukemia - Three months is too soon to judge a CML patient's response to Gleevec
Leukemia Therapy - Allo-SCT effective for pediatric CML patients
Leukemia Therapy - High stem-cell dose hastens platelet recovery after auto-SCT
Liver Cancer - Diagnostic test licensed from Toronto hospital
Liver Cancer - Rita Medical shares climb on encouraging test results for device
Liver Cancer Risk Factor - Hepatitis B immunization reduces incidence of hepatocellular carcinoma
Lung Cancer - Annual CT screening detects early-stage lung cancers
Lung Cancer - Antisense oligomer controls growth factor to halt non-small cell lung cancer
Lung Cancer - Company publishes preclinical results describing NC 381, an antitumor agent
Lung Cancer - Computer-aided detection system improves lung nodule detection
Lung Cancer - Enrollment completed in trial of Xyotax for high-risk patients
Lung Cancer - Female smokers are twice as likely as male smokers to develop deadly disease
Lung Cancer - New study reinforces need for early detection of lung cancer
Lung Cancer - New technology enhances lung cancer detection
Lung Cancer - Non-small cell lung cancer response to Taxol linked to P-glycoprotein
Lung Cancer - PET imaging displays transgene distribution in the lungs
Lung Cancer - Researchers quantify cancer risks from secondhand smoke
Lung Cancer - Risk for small cell lung cancer increases with some CYP3A alleles and smoke dose
Lung Disease - Detroit physician says lung scan may help smokers kick the habit
Lung Disease - International experts hope more attention goes to lung disease
Lymphoma Therapy - Stem-cell autotransplantation effective against nasal NK/T-cell lymphoma
Melamona - Vitamin C uses a caspase-independent pathway for apoptosis of melanoma cells
Melanoma - Gene explains why men are at higher risk of skin cancer
Mergers and Acquisitions - IMPAC to purchase PowerPath pathology, cancer registry information businesses
Metastasis - Cancer biopsies on the dot can clarify prognosis
Metastasis - Unraveling a protein, researchers uncover mechanics of anticancer agent
Molecular Biology - Chromosomes are "nibbled" before they fuse
Monoclonal Antibodies - Rituximab therapy holds promise in hematological disease, non-Hodgkin lymphoma
Muscular Disease - Partnership announced to find treatment for spinal muscular atrophy
Mutagenesis - A new assay detects genetic variants associated with colorectal cancer risk
Nerve Growth - Securin, low in fetal brain, correlates with lack of adult neural proliferation
Neurinomas - Acoustic neurinomas require monitoring, surgery before hearing damage occurs
New Products - NewsRx expands to 100 titles in Health Law and Business
Nutrition - "Musical fruit" rich source of healthy antioxidants; black beans highest
Obesity - Physicians tapped to help combat obesity
Oncology - Alpha-fetoprotein mRNA does not predict liver cancer in cirrhosis patients
Oncology - Angiogenesis peaks at two points during adenocarcinoma progression
Oncology - Biopharmaceutical NCE's expand oncology franchise
Oncology - Biopharmaceutical company partners with NIH to develop oncology compound
Oncology - Biotech company receives Canadian patent for potential cancer treatment
Oncology - New biomarker for advanced childhood brain cancer discovered
Oncology - Novogen granted patent for anticancer drug phenoxodiol
Oncology - Preclinical results positive for vascular targeting anticancer compound
Oncology - Revised guidelines show changes for breast cancer treatment
Oncology - Study data presented on agent for malignant glioma
Oncology - Study supports early use of drug in treatment of breast cancer
Oncology - The urokinase plasminogen activator system strengthens cancer metastasis
Oncology - VEGF-C links with low survival in esophageal squamous cell carcinoma patients
Orthopedic Surgery - Limb salvage techniques are effective in pediatric bone sarcomas
Pain Management - New product development program initiated for severe chronic pain
Patents - Broad patent granted for use of immune stimulatory CpG oligonucleotides
Personnel - Biopharmaceutical company names new executive for commercial development
Personnel - Prostate Cancer Foundation names new advisor and directors
Prostate Cancer - Elderly men receiving excessive prostate screening, study suggests
Prostate Cancer - Higher stromal density, desmin, SMA are indicators for recurrence-free survival
Pruritis - Pulsed dye laser therapy can resolve untreatable pruritis in ALHE patients
Radiation Therapy - 3-D image-guided radiation therapy system receives FDA clearance
Radiotherapy - Pelvic radiation dose must be altered if high atomic number prostheses are near
Recombinant Research - Myxococcus xanthus yields epothilone analogues with anticancer activity
Reimbursement - HealthBridge to manage Ganite maker's patient assistance program
Renal Cancer - Overexpressed von Hippel-Lindau tumor suppressor protein diminishes cancer
Sexually Transmitted Diseases - STDs could increase risk of cervical cancer
Skin Cancer - Drug can reduce sun damage by 50% for fair-skinned people
Skull Base Tumors - Microsurgery works as well or better than radiosurgery on skull base tumors
Solid Tumors - Preliminary phase I data presented on HYB2055
Stem-Cell Research - HOXB4 homeoprotein expands human hematopoietic stem cells
Stem-Cell Transplantation - HA-8 disparity linked to clinically insignificant risk in acute GVHD risk
Stem-Cell Transplantation - Long-term PBSC cryopreservation possible for germ cell cancer patients
Stock Market - Gene therapy company to list on the American Stock Exchange
Targeted Therapy - HPMA copolymer-bound doxorubicin effectively targets leukemia with monoclonal B1
Tobacco Use - Nicotine stimulates new vessel growth and encourages tumor growth
Transplantation - Adefovir offers rescue after hepatitis B virus reinfections of liver grafts
Tumor Therapy - Noninvasive surgical tool for the treatment of tumors being studied
Tumors - Progress reported on anticancer development program
X-Rays - Single cell irradiation in culture shows bystander nonirradiated cells also die
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