Published in Cancer Weekly, December 23rd, 2003
According to researchers in the United States, "this study was designed to evaluate the utility of positron emission tomography ( PET) to quantify the magnitude and spatial distribution of transgene expression after different methods of adenoviral vector delivery (with surfactant- and saline-based vehicles) within rat lungs."
"In all, 17 animals (eight in the surfactant group, nine in the saline group) were studied 3 days after intratracheal administration of a replication-incompetent adenovirus encoding a mutant herpes simplex virus-1 thymidine kinase (mHSV1-TK)enhanced green fluorescent...
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