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Pancreatic Cancer

Scientists announce long-sought mouse model of human pancreatic cancer

Published in Cancer Weekly, December 30th, 2003

Researchers at Dana-Farber Cancer Institute have created bioengineered mice that develop aggressive, fatal pancreatic cancer through the same genetic mishaps that cause the disease in humans.

The findings were posted online by the journal Genes and Development.

Because the mouse-model cancers start and progress along a path that closely resembles the disease's course in humans, the scientists believe it will be particularly useful in searching for telltale substances, or biomarkers, in the animals. These biomarkers could lead to a blood or urine screening test to catch the disease in an early and potentially curable stage in the mice and,...

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