Gynecology
Adenovirus-mediated suicide gene therapy destroys ovarian cancer cells
Published in Cancer Weekly, January 20th, 2004
"Telomerase is a ribonucleoprotein complex the function of which is to add telomeric repeats (TTAGGG)n to chromosomal ends, and it is known to play an important role in cellular immortalization. Telomerase is highly active in most tumor cells, yet not in normal cells. As such, it may have possible applications in cancer gene therapy," investigators in South Korea report.
"Telomerase consists of two essential components, telomerase RNA template (hTR) and catalytic subunit (hTERT). hTERT is expressed only in cells and tissues positive for telomerase activity, i.e.,...
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Source: Cancer Weekly (2004-01-20)
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