Hematology
Elevated cobalamin levels may indicate severe liver disease
Published in Cancer Weekly, January 20th, 2004
"Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin. Not surprisingly, a rise of the cobalamin concentration in serum is one of the diagnostic criteria for the latter two diseases," scientists writing in the journal Clinical Biochemistry report.
"The increase in circulating cobalamin levels is predominantly caused by enhanced production of haptocorrin. Several...
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Source: Cancer Weekly (2004-01-20)
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