Cancer Weekly

Testicular Cancer - Combination chemo offers high cure rates for most metastatic testicular cancer

Thyroid Cancer - Change of urinary glucocorticoids level may play a role in thyroid cancer

Bone Tumors - Telecommunication and telepathology optimizes treatment of malignant bone tumors

Tobacco Settlement - Counties want money for ill nursing home patients

Transgene Expression - Radiolabeled FIAU monitors the progress of cancer gene therapy

Tumor Ablation - Radiosurgery company gets Japanese regulatory clearance for CyberKnife

Tumor Marker - Silenced MAT-8 genes make prostate cancer cell proliferation decline

Tumor Suppression - Heterozygous disruption of the beclin 1 autophagy gene promotes tumorigenesis

Urethral Cancer - Report reviews the treatment of urethral cancer

Virology - Recombinant constructs revive p53 tumor-suppressor activity in tumor cells

Virology - Several genetic loci are known to regulate adenovirus-based gene therapy

Vulva Reconstruction - Modified VRAM flap can resurface a large vulvoperitoneal defect

Vulvar Pathology - Laser Doppler perfusion imaging can map vulva microcirculation

Metastasis - Simple microbes give insight into the development and spread of cancer

Brain Tumors - No environmental, chemical link found in Rohm and Haas brain tumor cases

Workers Compensation - Senator goes after compensation for Cold War-era nuclear workers

Breast Cancer - Areola-sparing mastectomy with immediate reconstruction is feasible

Breast Cancer - CAD workstation reference library to aid in early breast cancer detection

Breast Cancer - FDA grants clearance to market Ariol HerSight

Breast Cancer - Increased Bim mRNA and protein can cause apoptosis in breast cancer cells

Breast Cancer - Magnetic resonance imaging detects more tumors

Breast Cancer - Normal HC11 and ras-transformed mouse mammary cells are resistant retinoic acid

Breast Cancer - Pathologic study of reduction mammaplasty tissue should be performed routinely

Breast Cancer - Proteins and antibodies licensed for human cancer research

Breast Cancer - Radiotherapy improves survival after early stage, breast-conserving surgery

Complementary and Alternative Medicine - CAM treatments could hinder cancer treatment

Breast Cancer - Review of patient-tailored cancer treatment completed

Breast Cancer - Symposium calls for improved access to screening, treatment across Europe

Breast Cancer - Trial seeks patients in Southern California

Breast and Lung Cancer - Salivary-type neoplasms of the breast and lung need further molecular study

Bronchogenic Carcinoma - Exercise testing may predict surgical risk of pneumonectomy

Cancer Cell Biology - Scientists identify cell defects that limit immune system's impact on late-stage tumors

Cancer Databases - Center goal is to speed detection, treatment and prevention of cancer

Cancer Epidemiology - Using established epidemiological methods can best answer molecular questions

Cancer Incidence - Exposure to high levels of trichloroethylene may be increase risk of NHL

Cancer Metastasis - PTEN gene inactivation associates with breast cancer dissemination

Nasopharyngeal Cancer - TSLC1 gene is one of the target tumor suppressor genes of nasopharyngeal cancer

Cancer Outcomes - Patients enrolled in cancer trials do not necessarily fare better

Cancer Research - U.K. program for clinical research launched in London

Cancer Surgery - Excisional surgery for cancer cure may have adverse effects

Cancer Symptoms - Researchers summarize mechanisms underlying cancer-induced symptoms

Cancer Therapy - CRADA inked for pancreatic, ovarian, and lung cancer antibody development

Cancer Therapy - Company reports on mechanism for immunotherapy cure of prostate cancer

Cancer Therapy - DFMO did not improve outcomes in superficial bladder cancer study

Cancer Therapy - Patent granted for humanized CEA antibody conjugates

Cancer Therapy - The cytocidal gene construct rexin-G arrests pancreatic tumor growth

Oncology - Combined gene regulatory elements select for melanoma suicide gene expression

Cancer Therapy - Therapies that control VEGF production look appealing for treating cancer

Cancer Vaccine - Cancer vaccine delivers antigen to dendritic cells

Carcinogenesis - Arsenic is associated with increased cancer incidence

Cell Transduction - A unique coculture system improves in vitro investigations of gene therapy

Cervical Cancer - Cervical cancer staging is based on clinical, anatomic disease extent

Cervical Cancer - Cervical neoplasia is an HPV-associated malignancy

Cervical Cancer - Chemotherapy for carcinoma of the cervix has improved outcomes

Cervical Cancer - Combined therapy is standard treatment for Stage IIB-IVA cancer of the cervix

Cervical Cancer - DNA testing for HPV complicates management of atypical cervical cytology

Cervical Cancer - Hong Kong diva's death inspires Singapore women to screen for cervical cancer

Oncology - Hepatitis B virus X protein is involved in the etiology of liver cancer

Cervical Cancer - Role of injectable progesterones in cervical cancer remains unconfirmed

Cervical Cancer - System for cervical cytology reporting is updated

Cervical Cancer Screening - Self-sampling and direct sampling for HPV compared

Chemotherapy - Helsinn signs licensing agreement for palonosetron with Japanese firm

Child Protection - Utah legislators to make parents' rights an 'emotional' issue

Chronic Myeloid Leukemia - Marrow fibrosis indicates therapy failure in chronic myeloid leukemia

Cochlear Implants - Penetrating electrode auditory device successfully implanted

Collaborations - Alliance with Baxter to discover anti-MIF antibody

Collaborations - Metabasis joins forces to develop hepatitis C therapeutic

Collaborations - New cancer vaccine program launched

Addiction Medicine - Alcohol has a dose-dependent effect on endothelial adhesion molecules

Colon Cancer - Eloxatin approved in U.S. for treatment of metastatic colorectal cancer

Colon Cancer - Larger colon tumors need more injected dye to identify sentinel lymph nodes

Colorectal Cancer - BRAF mutations associated with sporadic colorectal cancers

Colorectal Cancer - Beta-catenin has a role in invasion and metastasis of colorectal carcinomas

Colorectal Cancer - Clinical trials use gene therapy for GI cancer

Colorectal Cancer - Increased fiber intake is associated with a smaller risk of colorectal adenomas

Angiogenesis - Patent granted for antiangiogenic treatments using VEGF inhibition

Colorectal Cancer - Tumor-related Rac1b not regulated by Rho-GDP dissociation inhibitors

Corporate Update - Genome5000 program has yielded more than 40 drug discovery programs

Corporate Update - Oncology drug maker reports initial guidance for 2004

Courts - Victims of cancer drug dilution scheme to receive checks soon

Cutaneous Lymphoma - Researchers propose guidelines for managing primary cutaneous T-cell lymphomas

Cutaneous Melanoma - p53 Arg/Arg genotype linked to higher risk of cutaneous melanoma over age 50

Depression - Nurses can play role in helping cancer patients keep the blues at bay

Diet and Cancer - Researchers report common and country-specific dietary patterns in Europe

Dietary Cancer Exposure - Polycyclic aromatic hydrocarbons in foods increase cancer risk

Drug Resistance - Liposome-based approaches can target drugs to tumor tissue

Anticancer Therapy - Recent developments in antitumor taxoids reviewed

End-of-Life Care - Psychologists can be helpful for end-of-life decisions

Endometrial Cancer - Surgical staging directs appropriate use of radiotherapy

Environmental Health - Study: Agent Orange linked to cancer risk

Epidemiology - Hepatitis B virus pre-S mutants flourish in countries with HBV endemicity

Finance - Genomic-marker company completes $5.4 million series A financing

Gastric Cancer - A PI3K inhibitor holds promise as an antitumor agent for gastric carcinoma

Gastroenterology - Gemcitabine halts ascites formation in patients with pancreatic cancer

Gastroenterology - Thymidylate synthase antisense blocks the oncogenic properties of colon cancer

Gene Expression - Gene-disabling technique simplified by medical school team

Gene Expression - Roche to license Eberwine linear RNA amplification technologies