Cancer Weekly
Susan Hasty, Publisher
Table of Contents . . . February 17th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cancer Weekly | Other Publications
Cancer Therapy - Researchers discover that a virus can naturally target and kill tumors
Anti-thrombotic Therapy - Low-molecular-weight heparins reduce cancer mortality rate
Imaging - Incidental PET findings may reveal undetected cancer
Imaging Technology - System used to visualize tumors in cancer patients installed at NIH center
Informed Consent - Researchers call for better communication strategies between physicians, parents
Internet - Americans view Internet as an important health resource, survey finds
Laryngectomy - Researchers present 10-year experience with post-laryngectomy voice restoration
Legal Issues - Cigarette maker loses Supreme Court appeal
Legal Issues - Farmed salmon industry faces lawsuit over cancer-causing chemicals in fish
Legal Issues - Former Colorado mine workers sue over contamination
Legal Issues - U.S. Attorney requests dismissal of citations in medical marijuana case
Leukemia - Adolescents with ALL may have better outcomes from pediatric oncologists
B-Cell Lymphoma - Extranodal versus nodal disease at presentation may be clinically important
Leukemia - Co-expression of WT1 and MDR1 genes in AML could help determine treatment
Leukemia - FDA approval granted for liquid form of cytarabine injection
Leukemia Diagnostics - WT1 is a poor marker of post-SCT minimal residual disease
Leukemia Pathogenesis - Transient myeloid progenitors can underlie leukemogenesis
Leukemia Therapy - Auto-SCT with costimulated T-cell infusion effective against refractory CML
Leukemia Therapy - Campath-1H does not protect against GVHD in CLL patients
Liver Cancer - Those treated for HCV-related cancer have better odds if inflammation declines
Lung Cancer - "Rolling" NDA submission initiated for Tarceva
Lung Cancer - FDG-PET is better for diagnosing lung cancer, study finds
Bladder Cancer - Patterns of recurrence should help create follow-up programs for bladder cancer
Lung Cancer - LungAlert cancer test data accepted for presentation
Lung Cancer - National lung screening trial reaches goal of 50,000 participants
Lung Cancer - Researchers create "cluster bombs" for drug delivery
Lung Cancer Therapy - Multimodal treatment effective for elderly SCLC patient
Lung Tumors - Video-assisted anatomic mediobasal segmentectomy of lung is successful
Lymphoma - FDG-PET performed early during chemotherapy may predict lymphoma course
Lymphoma - Quality of life issues are important considerations in cutaneous T-cell lymphoma
Lymphoma - Transjugular biopsy useful for primary cardiac lymphoma diagnosis
Lymphoma Therapy - High-dose chemo with CD34+-APBSCT effective against nasal NK/T-cell lymphoma
Malignant Neoplasms - Zilver 518 biliary stent launched following FDA approval
Bladder Cancer - Regular follow-ups are necessary for superficial bladder cancer patients
Market Analysis - Biotech firms will speed development of more cancer medicines
Medicine - Extract from honeybee hives downregulates angiogenesis and tumor metastasis
Melanoma - Active-specific immunization against melanoma reviewed
Melanoma - Children and adolescents with melanoma should be enrolled in clinical trials
Melanoma - UVB irradiation can induce hMLH1 and hMSH2 gene mutations
Melanoma Vaccine - Poxvirus used for delivery of stimulatory molecules to melanoma tumors
Mesothelioma - U.K. faces asbestos epidemic
Metastasis - Loss of TIP30 heightens susceptibility to tumor development
Multiple Myeloma - High-, intermediate-dose melphalen regimens compared in multiple myeloma
Bladder Cancer - The phosphatidylinositol-3 kinase pathway may control invasive bladder cancer
Multiple Myeloma - Velcade recommended for European marketing approval
Myelodysplastic Syndrome - Combination regimen active in allogeneic bone marrow transplant MDS patients
Myelodysplastic Syndrome - Novel reduced-intensity SCT safe and effective for MDS treatment
Nasopharyngeal Cancer - Researchers study stress and other problems in nasopharyngeal carcinoma patients
Neuroblastoma - Live-attenuated poliovirus may be of use in treating neuroblastoma
Neuroscience - Mutated tau gene transfer fashions models for the study of neurodegeneration
Non-Hodgkin Lymphoma - European Commission approves Zevalin radioimmunotherapy
Non-Hodgkin Lymphoma - Hair dye use increases risk of lymphoma
Oncogenesis - Hepatoma-derived growth factor fuels tumorigenesis through angiogenic induction
Oncogenesis - Interplay between hypoxia- and estrogen-dependent signaling rules breast cancer
Blood Vessels - Peptide demonstrates tumor inhibition in preclinical models
Oncogenesis - Patients with hepatitis B and C coinfections have a slightly higher cancer rate
Oncology - CHFR predicts the sensitivity of gastric cancer to microtubule inhibitors
Oncology - Four heat shock proteins are biomarkers for HCV-related liver cancer
Oncology - Monocyte chemoattractant protein-1 sensitizes cervical cancer to cisplatin
Oncology - Telomerase inhibition is a unique strategy for treating hematological cancers
Oncology - The new agent LY317615 lowers plasma VEGF levels in murine cancer models
Oral Mucositis - Study compares oral mucositis treatments in children undergoing chemotherapy
Organ Donation - People with malignant gliomas can become organ donors
Pancreatic Cancer - Liposomal suicide gene therapy attacks peritoneal cancer
Pancreatic Cancer - Localizing mucin expression might be predictive of pancreatic cancer outcome
Bone & Soft-Tissue Tumors - Patients remain fatigued after treatment for bone and soft tissue tumors
Patents - Electroporation therapy patents announced; company provides update
Patents - New patents protect applications related to inhibiting cell proliferation
Pediatric Leukemia - Infection-related complications remain a serious problem in children with AML
Pelvic Reconstruction - CT-based navigation is warranted in screw fixation of the pelvis
Pelvic Sarcomas - Report describes computed-assisted hemipelvectomy and prosthesis implantation
Personnel - Ablation device company makes board appointments
Personnel - Gunnar Casserstedt joins Connecticut biotech as CFO
Personnel - Mark Ahn named CEO and president of development-stage biopharmaceutical company
Personnel - Michael Markels to lead sales and marketing for neuropathic pain company
Bowel Obstruction - Differentiating true bowel obstruction from pseudo-obstruction is critical
Phosphodiesterase - Thalidomide analogs control tumor growth through vessel suppression
Prostate Cancer - A randomized trial studies choice of treatment for prostate cancer
Prostate Cancer - Brachytherapy can cause devastating complications in prostate cancer patients
Prostate Cancer - Cryotherapy may play a bigger role in future treatment of prostate cancer
Prostate Cancer - Detection of complexed PSA markers in prostate cancer is promising
Prostate Cancer - Guidelines are needed for transrectal, ultrasound-guided prostate biopsies
Prostate Cancer - Intraoperative nerve stimulation with prostatectomy may predict ED
Prostate Cancer - McKesson chosen as preferred specialty distributor for Plenaxis
Prostate Cancer - New guidelines for drug studies for relapsed patients published
Prostate Cancer - Sulforaphane, found in cruciferous vegetables, may inhibit prostate cancer
Brain Tumors - Researchers describe surgical approaches to posterior third ventricular tumors
Prostate Cancer - Weekly calcitriol combined with docetaxel favors men with advanced cancer
Prostate Cancer - Younger men at high risk for prostate cancer should undergo screening
Pulmonary Medicine - The additive effects of TRAIL and p53 gene therapy diminish cancer cell growth
Radiology - Intermittent bolus-contrast power Doppler sonography relays tumor status
Radiology - U.K. study quantifies cancer risk from diagnostic X-rays
Rhabdomyosarcoma - Orbital rhabdomyosarcoma is chemo- and radiosensitive
Rhabdomyosarcoma - Web-based decision support tool can match rhabdomyosarcoma patients to trials
Seminoma - Patients with recurrent seminoma require greater follow-up
Skin Cancer - Photodynamic therapy for basal skin cancer associated with recurrence
Smoking - Class action claim regarding health risks of 'light' cigarettes turned down
Brain Tumors - Study finds no prolonged survival benefit of thermoradiotherapy in brain tumors
Smoking Cessation - Smokers who try to stop can benefit from medications and counseling
Stem-Cell Transplantation - Features and treatment of vaginal GVHD described
Stem-Cell Transplantation - Inflammatory myofibroblastic tumors reported in pediatric SCT recipients
Stem-Cell Transplantation - T-cell lymphoproliferative disorders possible after auto-SCT
Stem-Cell Transplantation - Unrelated cord blood transplants feasible for adults
Stereotactic Radiosurgery - Understanding stereotactic radiosurgery is critical for oncology nurses
Technology - e-Science project takes on some of the grand challenges in medical research
Testosterone Replacement - "No compelling evidence" of prostate cancer, heart disease risk found in study
Tobacco - Higher tobacco tax proposed as cancer funding source
Tumor Suppressor - Controlling p53 functions may be a target for cancer therapy
Retinoblastoma - First successful embryo biopsy for deadly genetic cancer performed
Brain Tumors - Surgical resection is possible in most cases of metastatic tumors
Weight Loss - Antiobesity drugs could increase risk of colorectal cancer
Wilms Tumor - Study reviews the management of recurrent Wilms tumor
Brain Tumors - Various surgical approaches to tumors of the lateral ventricle are discussed
Breast Cancer - Computer-aided technology partners with mammography system
Breast Cancer - New mode of action discovered for tamoxifen
Breast Cancer - Researchers update the medical management of advanced breast cancer
Breast Cancer - Social support important for older breast cancer survivors
Breast Cancer - Swedish HRT trial stopped early due to unacceptable risks
Breast Cancer - Unmitigated communion is linked to poor adjustment to breast cancer
Breast Cancer - Virtual reality helps patients cope with chemotherapy
Breast Cancer Therapy - Cord blood can be excellent source of antitumor T cells
Mantle Cell Lymphoma - Researchers hunt for new treatments to rare cancer
Burn Medicine - Skin regeneration not limited to epidermal stem cells
Cancer Caregivers - Telephone support proves helpful for people caring for patients with cancer
Cancer Prevention - Cancer prevention consortium announced in Pennsylvania
Cancer Research - c-Jun NH2-terminal kinase inhibition arrests growth in multiple myeloma cells
Cancer Risk - Scientists estimate cancer risk from X-rays is low in most countries
Cancer Screening - Breast augmentation may interfere with mammography interpretation
Cancer Suppression - Engineered zinc finger transcription factors restrict glioblastoma VEGF-A
Cancer Survival - Cancer survival survey of Europeans aged 15-24 shows youngest fare worse
Cancer Symptoms - MDASI scale is cross-culturally valid
Cancer Therapy - CPMP issues positive recommendation for Paxene
Oncology - Transcription factor Ets-1 associates with the malignant phenotype of melanoma
Cancer Therapy - Cancer vaccine using low affinity epitopes proves successful in mice
Cancer Therapy - Collaboration means more Los Angeles patients can access clinical trials
Cancer Therapy - Direct and indirect angiogenesis inhibitors work better when combined
Cancer Therapy - Gamma-linolenic acid infusion occludes vessels that feed tumors
Cancer Therapy - Human papillomavirus L1 renders cells susceptible to NK-mediated destruction
Cancer Therapy - PI-88 melanoma phase II trial begins
Cancer Therapy - Research: MPC-6827 causes tumor regression in pancreatic cancers
Cancer Therapy - Tamoxifen blocks vascular endothelial growth factor in breast cancer tumors
Cancer Therapy - Z-100 augments radiotherapy efficacy in melanoma patients
Cancer Vaccine - DNA induces T helper type 1-mediated responses in antigen-primed mice
Renal Cancer - Tumor irradiation improves cytokine gene therapy targeting murine kidney cancer
Cancer Vaccine - Researcher reviews novel cancer vaccines
Cervical Cancer - French government approves reimbursement of HPV testing
Cervical Cancer - New drugs are needed to improve response rate of cervical cancer
Cervical Cancer - Study compares factors contributing to cervical cancer in the U.S. and Venezuela
Chemotherapy - Assessing five common side effects of chemotherapy is beneficial for patients
Chemotherapy - The long half-life of palonosetron may help prevent late chemotherapy emesis
Children's Health - Study: Better communication needed for parents of kids in research
Collaborations - Alliance to conduct preclinical testing of gene-silencing agent
Collaborations - Commercialization partnership signed for oncology drug
Colon Cancer - ABX-EGF enters pivotal trial in advanced colorectal cancer patients
Acute Myeloid Leukemia - An oral combined regimen for AML had less toxicity and hospitalization
Colon Cancer - Beer or malt intake inhibits azoxymethane-induced colonic carcinogenesis in rats
Colon Cancer - COX-2 plus fluorinated pyrimidines reduced liver metastasis in the mouse
Colon Cancer - Cancer blood test receives certification
Colon Cancer - Eloxatin submitted in U.S., Europe as adjuvant treatment
Colon Cancer - High levels of certain protein in blood associated with development of colon cancer
Colon Cancer - Kentucky votes on bill requiring mandatory coverage for colon cancer screenings
Colon Cancer - Molecular events are responsible for colorectal cancer development
Colonoscopy - Screening once avoided now requested by health-conscious boomers
Colorectal Cancer - IL-6 levels are increased in malnourished patients with colorectal cancer
Colorectal Cancer - Plant-produced colorectal cancer antigen developed
Adolescent Cancer - Adolescents with cancer have specific needs and requirements
Colorectal Cancer - Reach of sigmoidoscopies inadequate in many older women
Colorectal Cancer - Risk factors for colon and rectal cancer appear to differ by subsite
Cutaneous Lymphoma - Primary cutaneous B-cell lymphomas may be underdiagnosed in the U.S.
Depressive Disorders - Psychological problems are common among gynecologic and obstetric patients
Dermatology - Topical immunomodulators used to treat atopic and eczematous dermatitis
Disease Associations - Meta-analysis concludes breast implants don't increase brain cancer risk
Disease Associations - Study concludes that abortions do not increase breast cancer risk
Drug Development - DPTH might be able to discourage angiogenesis
Drug Development - Plant jasmonates have antiparasitic as well as anticancer activity
Drug Development - Suppressed protein kinase B signals augment breast cancer heat treatment
Adolescent Cancer - Teenage cancer patients are characterized as a separate patient group
Endocrinology - Combined gene therapy staunches medullary thyroid carcinoma
Endometrial Cancer - IGF-binding protein 1 linked to endometrial cancer risk
Enzymology - Matrix metalloproteinases lead specific functions in metastatic melanoma
Esophageal Cancer - Survival for esophageal cancer remains poor despite treatment advances
Finance - Cancer-drug maker announces pricing of common stock public offering
Finance - INEX makes milestone payment to former partner
Finance - Vascular-focused company completes sale of common stock
Gastric Surgery - Researchers discuss the benefits of robot-assisted gastric surgery
Gastroenterology - Interferon lowers the risk for liver cancer in patients with chronic hepatitis C
Gastroenterology - Transgenic mice offer a new way to study hepatitis C virus immunopathology
Angiology - Growing evidence suggests angiopoietin-1 stabilizes newly formed tumor vessels
Genetic Testing - African American and Latina women are concerned about genetic testing attitudes
Glioblastoma - Survival is unremarkable in cancer patients given suramin and radiotherapy
Gynecologic Cancers - New brachytherapy applicator available for treating uterine, cervical cancer
Gynecologic Surgery - Bowel preparation prior to gynecological surgery may be unnecessary
Hematologic Malignancies - SGN-30 advanced to phase II clinical study
Hematologic Malignancies - Triapine clinical studies initiated under collaboration
Hematologic Toxicities - Hematopoietic growth factors can reduce neutropenia and anemia from chemotherapy
Hematology - Conditional TRAIL-expressing T cells induce apoptosis in B-cell lymphomas
Hepatocellular Cancer - Radiofrequency ablation and transcatheter chemoembolization are used for HCC
Human Papillomavirus - Denaturing high-performance liquid chromatography can detect HPV types
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