Published in Cancer Weekly, February 17th, 2004
"Caffeic acid phenethyl ester (CAPE) derived from honeybee propolis has been used as a folk medicine and has several proven biological activities. The present study investigated the effect of CAPE on angiogenesis, tumor invasion, and metastasis. A cytotoxicity assay of CAPE in CT26 colon adenocarcinoma cells showed a dose-dependent decrease in cell viability but no significant influence on the growth of human umbilical vein epithelial cells (HUVEC)," scientists in Taiwan report.
"A low concentration of CAPE (1.5 microgram/mL) inhibited 52.7% of capillary-like tube formation...
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