Oncology
Monocyte chemoattractant protein-1 sensitizes cervical cancer to cisplatin
Published in Cancer Weekly, February 17th, 2004
"Cervical cancers at advanced stages or with recurrent status are mainly treated by platinum-based chemotherapy, such as cisplatin. However, a novel strategy to reduce the minimally effective dose is required to prevent severe adverse effects that limit the effectiveness of the treatment. Monocyte chemoattractant protein-1 (MCP-1) is a subtype of chemokines that can promote monocyte/macrophage infiltration and enhance their phagocytosis at not only sites of inflammatory lesions but also of tumors," scientists in Japan report.
"The present study applies MCP-1-based gene...
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Source: Cancer Weekly (2004-02-17)
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