Published in Cancer Weekly, February 24th, 2004
According to a study from the United States, "Loss of heterozygosity and allelic imbalance data have shown that there are two distinct regions of loss on chromosome 18q associated with the progression of prostate cancer (CaP)."
"To investigate the functional significance of chromosome 18q loci in CaP, we utilized the technique of microcell-mediated chromosome transfer to introduce an intact chromosome 18 into the human prostate cancer cell line, PC-3. Three of the resulting hybrid lines were compared to the PC-3 cells in vitro and...
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