Published in Cancer Weekly, March 2nd, 2004
According to published research from the United States, "Massive hyperdiploidy (>50 chromosomes) and tetraploidy (4n) are rare cytogenetic abnormalities in myelocytic malignancies, and their significance is unknown."
"We report on 11 patients with AML and 2 patients with a myelodysplastic syndrome (MDS) with massive hyperdiploidy (10 patients) or tetraploidy (3 patients) seen at our institution over a 12-year period," wrote R.V. Iyer and colleagues, Roswell Park Cancer Institute, Department of Medicine.
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