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Computational Biology

New mathematical algorithms might help diagnose cancer

Published in Cancer Weekly, March 2nd, 2004

Dartmouth researchers have developed an algorithm that might someday be used to analyze blood for diagnostic purposes. Using data from a mass spectrometer, a device that generates a molecular fingerprint of biological samples, the Dartmouth team's calculations can distinguish healthy blood from diseased blood.

This study by Ryan Lilien, a Dartmouth MD/PhD student, Hany Farid, assistant professor of computer science, and Bruce Donald, the Foley Professor of Computer Science, appeared in the Journal of Computational Biology.

"Our algorithm, named Q5, works on the assumption that the molecular composition of the blood changes between healthy and...

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