Cancer Weekly

Gastroenterology - VEGF might be a predictor of gastric cancer transformation

Gastrointestinal Tumors - Targeted molecular autofluoresence can detect murine intestinal adenomas

Gene Transfer - A new gene carrier steers interleukin-12 to solid tumors

Genital Cancer - Estrogen affects ultrastructure of testis germinal epithelium in Wistar rats

Germ Cell Tumors - Temozolomide proves ineffective in cisplatin-refractory germ cell tumors

Gynecological Cancer - Image fusion helps resolve discrepant findings between FDG-PET and MRI/CT

HIV/AIDS Treatment - New data suggest potential for once-daily dosing regimen of Kaletra

Head and Neck Cancer - Angiogenesis is difficult to quantify in oral cancers

Head and Neck Cancer - The angiogenic switch is an early event in esophageal squamous cell carcinoma

Hepatitis - VIR201 data presented at conference

Hepatocellular Carcinoma - Splenectomy in patients with HCC and secondary hypersplenism can improve staging

Hepatocellular Carcinoma - Surgery for biliary tumor thrombus prolongs survival in hepatocellular cancer

Hodgkin Disease - Modified cytotoxic T cells ferry interleukin-12 to local tumor sites

Hodgkin Lymphoma - Hodgkin lymphoma treatment should focus on improving late morbidity, mortality

Hyperparathyroidism - Some types of familial isolated hyperparathyroidism have unknown cause

Imaging - Medical Media Systems buys tumor-imaging technology

Immunoassays - Eleven diagnostic assays approved for hepatitis, PSA, alpha-fetoprotein

Information Technology - CIBEX contains experimental data on gene expression research

Information Technology - Researchers develop a retroviral tagged cancer gene database

Information Technology - SNP500Cancer database helps researchers map diseases

Kaposi Sarcoma - Mechanisms of HHV-8 IL-6 mimicry determined

Leukemia - GATA1 mutations are common children with Down syndrome

Leukemia - Generic Purinethol tablets receive marketing clearance

Leukemia - Immature B cell cancers generate proangiogenic growth factor

Leukemia Pathogenesis - E2a/Pbx1 triggers proliferation of SCF-dependent pro-T cells

Leukemia Therapy - BAVC SCT conditioning comparable to BuCy regimen

Leukemia Therapy - Novel regimen effective for JMML patients without stem-cell donors

Leukemia Therapy - SCT with voriconazole treatment feasible for AML with pulmonary aspergillosis

Leukemia Therapy - Utility of STR markers for post-SCT chimerism evaluated

Liver Cancer - Management of inferior vena cava injury during hepatectomy is discussed

Lung Biopsy - Contrast-enhanced sonography guides transthoracic biopsy of lung lesions

Lung Cancer - Lung cancer compound phase II trial commences

Lung Cancer - Peroxisome proliferator-activated receptor-gamma activation inhibits NSCLC

Lymphoma Therapy - Mantle cell lymphoma treatment reviewed

Medicare - Cancer experts ask Congress to hold chemo reimbursement rates at 2004 level

Melanoma - Data on autologous cell vaccine published

Melanoma - Nodal nevi are more frequent in patients with melanoma-associated cutaneous nevi

Melanoma - The Libechov minipig model is suitable for studying human melanoma

Mergers and Acquisitions - Harvard inks letter of intent to acquire assets of antibody development company

Mesothelioma - CT, MR, and PET imaging should be used to assess malignant pleural mesothelioma

Metastatic Cancer - CT and MRI can identify inferior vena caval thrombus in metastasis to the kidney

Myelodysplastic Syndromes - Low-dose topotecan in myelodysplastic syndromes has no effect

Myelodysplastic Syndromes - Treatment monitoring in MDS patients reviewed

Neuroendocrine Tumors - Genetic abnormalities are related to neuroendocrine tumor progression

Neuroendocrine Tumors - Specialty nurses benefit patients with neuroendocrine tumors

Non-Hodgkin Lymphoma - Hair dye use increases blood-cancer risk in women

Oncogenesis - The proto-oncogene hSecurin is highly expressed in some myeloid leukemias

Oncology - COX-2-derived prostaglandin E-2 is a potent breast cancer stimulant

Oncology - Effusions from patients with cancer harbor high levels of angiostatin

Oral Cancer - Decades of surgical, therapeutic advances have improved oral cancer survival

Oral Cancer - Smoking black tobacco and drinking alcohol increases risk of oral cancer

Osteosarcoma - Noninvasive approach to salvaging limbs helps young bone cancer patients

Ovarian Cancer - Anticancer drug Phenoxodiol produces promising results

Ovarian Cancer - COX-2 and angiogenic status yield ovarian carcinoma prognosis

Ovarian Cancer - Experimental drug used to treat recurrent disease shows promising results

Ovarian Cancer - Guidelines help ovarian cancer patients receive proper treatment referrals

Ovarian Cancer - Raf is necessary for Ras transformation of ovarian epithelial cells

Packaging - Agreement inked for prefilled dual chamber pharmaceutical mixing device

Pancreatic Cancer - Multidetector CT may improve imaging of pancreatic adenocarcinoma

Patents - Locus Pharmaceuticals wins drug-design patents

Patents - Patent issued for exosome technology - a new approach to immunology

Pediatric Cancer - Computer program aids chemotherapy regimen planning

Pediatric Cancer - MYCN oncogene mediates multidrug resistance-associated protein in neuroblastoma

Pelvic Reconstruction - Transpelvic vertical rectus flaps can cover complex perineal wounds

Personnel - Ashleigh Palmer named new chief business officer at biotech company

Personnel - Company names new chief technology officer and VP, development

Personnel - Daniel S. Lynch named CEO and director of Erbitux maker

Product Licensing - Nuvelo licenses rNAPc2, an anticoagulant

Prostate Cancer - Beta-catenin nuclear signaling molecule may be an oncogene in prostate cancer

Prostate Cancer - New view of recurrent prostate cancer proposed

Prostate Cancer - Sulforaphane reduces PC-3 xenografts in vivo in a murine model

Prostate Cancer - Vibroacoustography holds promise for brachytherapy metal seed imaging

Proteomics - Divalent cations augment endostatin after heparin and heparan sulfate binding

Radiation Oncology - New technology may help doctors more accurately target tumors

Skin Cancer - Link between tanning devices and skin cancer still unproven but worrisome

Skin Cancer - More patients protect themselves from the sun after skin cancer surgery

Skin Cancer - Sun exposure behaviors correlated with dose of ultraviolet radiation received

Stem-Cell Transplantation - Post-SCT immunological recovery similar in CLL, NHL patients

Teratomas - Gonadal teratoma behavior depends upon tumor site and patient age

Thyroid Cancer - Ultrasonography can help guide fine needle aspiration biopsy of thyroid nodules

Thyroid Carcinoma - Quality of life lower during periods of hypothyroidism in thyroid carcinoma

Tumor Growth - Amine oxidases and tumors are correlated

Vaccine Development - Tumor-pulsed dendritic cells activate antitumor protection

Vascular Dilatation - Vascular dilatation in the pelvis can be due to obstruction or tumor

Vector Delivery - Single photon emission computed tomography tracks genes in minute lung tumors

Vector Development - Coupled carriers may offer a better way to transfer genes to tumor cells

Virology - A new expression vector augments the cloning of full-length HBV genomes

Virology - Multiply modified retroviral vectors carry high titers in lab evaluations

Wasting Syndrome - Ghrelin upregulated in cachectic nude mice bearing human melanoma cells

Women's Health - Clip markers can migrate after imaging-guided directional vacuum-assisted biopsy

Women's Health - Digital mammography has not yet improved cancer detection rates

Wound Care - Ascorbic acid modulates the effects of radiation-delayed wound healing