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HIV/AIDS Treatment

New data suggest potential for once-daily dosing regimen of Kaletra

Published in Cancer Weekly, March 9th, 2004

New data, presented at a scientific meeting in San Francisco, California, suggest that an HIV treatment regimen based on a once-daily dose of Abbott Laboratories' protease inhibitor Kaletra (lopinavir/ritonavir) had comparable viral suppression when compared to a twice-daily dose through 1 year (48 weeks) in patients new to treatment.

Currently, the adult recommended dosage of Kaletra is 400/100 mg (3 capsules or 5 milliliters) twice daily with food.

"Patients taking a once-daily Kaletra-based regimen showed comparable results to the twice-daily regimen in terms of virologic suppression," said Joseph Gathe, Jr., MD, FACP, lead investigator and...

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