Autoimmune Disease

Scientists produce extended serum half-life of human antibodies

Published in Cancer Weekly, March 16th, 2004

Protein Design Labs, Inc., (PDL) announced that the Journal of Biological Chemistry has published results of research in which PDL scientists produced a significant extension of the serum half-life of human antibodies.

The article is entitled "Engineered Human IgG Antibodies with Longer Serum Half-lives in Primates."

Human and humanized antibodies typically have a serum half-life of approximately 3 weeks in humans. Maintaining serum half-life represents an important element of determining and providing appropriate drug exposure in the body.

PDL researchers, led by Naoya Tsurushita, PhD, engineered variants of human IgG...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Cancer Weekly

Source: Cancer Weekly (2004-03-16)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry