Published in Cancer Weekly, March 16th, 2004
According to scientists writing in the journal Cancer Letters, "we examined the functional role of clusterin in chemotherapy-induced apoptosis and tested whether antisense transfection targeted against clusterin enhances the chemosensitivity in human bladder cancer cells in vitro. Clusterin mRNA and protein expression of 253J cells, a human bladder carcinoma cell line, after treatment with cisplatin were measured by reverse transcriptase-polymerase chain reaction (RT-PCR) and Western blot analysis. Clusterin expression and cell growth were compared between 253J cells transfected with a...
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