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Prostate Cancer

Nadir PSA can predict progression to androgen-independent prostate cancer

Published in Cancer Weekly, March 23rd, 2004

Two consecutive increases of prostate-specific antigen (PSA) indicate androgen-independent progression (AIP) in advanced and metastatic prostate cancer.

"The objective of our study was to analyze the value of PSA levels before and after androgen suppression to predict the time to AIP in patients with advanced and metastatic prostate cancer," scientists in Spain report.

"A series of 283 prostate cancer patients under androgen suppression as a single treatment was studied. The disease was locally advanced in 98 patients and metastatic in the remaining 185," wrote J. Morote and colleagues, University of Barcelona, Hospital General Valle Hebron.

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