Colorectal Cancer

New way of increasing efficacy of chemotherapy described

Published in Cancer Weekly, March 23rd, 2004

INSERM and CNRS research scientists and doctors at the Institut Curie have demonstrated the influence of the status - mutated or functional - of the tumor suppressor gene p53 in the response of colorectal cancer to chemotherapy.

Tumors in which the p53 gene is mutated respond less well to treatment. However, by adding another agent, researchers at the Institut Curie have succeeded in increasing the efficacy of chemotherapy in mice bearing human cancer xenografts.

The presence of a mutation in the p53 gene could explain the resistance to treatment of certain tumors, whence interest in developing therapeutic approaches better suited to the genetic...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Cancer Weekly

Source: Cancer Weekly (2004-03-23)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry