Cancer Weekly
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Breast Cancer
Male carriers of germline mutations in BRCA2 are at increased risk for cancer
April 6th, 2004
Men with BRCA2 mutations are at greater risk for cancer, especially before age 65, researchers report. "Major risks conferred by BRCA1 and BRCA2 in women are for cancers of the breast, ovary, fallopian tube, and peritoneum. Male carriers of mutations in BRCA1 or BRCA2 are also susceptible to cancer; however, their risks remain poorly understood and their optimal clinical management has not yet been defined," scientists in the United States report. "This article reviews studies that estimate risk associated with mutations in BRCA1 or BRCA2 with a focus on the cancer sites most relevant to men. Male BRCA1 mutation carriers are at increased risk of...
Source: Cancer Weekly (2004-04-06)
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