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Leukemia

Combo of two natural toxins may be novel treatment for blood cancer

Published in Cancer Weekly, April 6th, 2004

Johns Hopkins Kimmel Cancer Center scientists have discovered why arsenic has long been a successful way to treat certain leukemias, and in the process have shown that a combination of the poison and a second naturally occurring toxin may provide a potent new therapy for them.

The researchers discovered that arsenic, a naturally occurring element, actually activates the same cellular self-destruct mechanism as a compound called bryostatin, a toxin found in coral-like aquatic organisms. The findings were reported in the March 15, 2004, online issue of Proceedings of the National Academy of Sciences USA.

Used for centuries for a variety of...

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