Susan Hasty, Publisher
Table of Contents . . . April 13th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cancer Weekly | Other Publications
Brain Cancer - New tumor suppressor may play important role in deadly brain tumors
Developmental Biology - Tumorigenesis and organogenesis have shared features
Breast Cancer - First murine experimental model developed of human breast cancer
Cancer Diagnostics - TCR-V-beta FACS can identify peripheral blood TCLPD involvement
HIV/AIDS Cancer - Bone marrow features in AIDS patients characterized
Leukemia - Genes predict response of adult patients to chemotherapy
Acute Promyelocytic Leukemia - CD2 expression by APL cells linked to poor prognosis
Aging Skin - Chemopreventive effects of green tea said to delay aging of skin
Anti-Infectives - Caspofungin effective for pediatric cancer patients, bone marrow recipients
Arthritis Therapy - Methods otrexate may be lymphoma trigger in patients with highly active RA
Asbestos - Senators call for a national asbestos ban
Autoimmune Disease - Researchers say chemo drug may help people with autoimmune diseases
Bile Duct Tumors - Orphan drug designation granted for anticancer agent XL119
Bladder Cancer - Automated version of ImmunoCyt/uCyt+ bladder cancer test launched
Breast Cancer - Application submitted for approval of breast cancer diagnostic
Breast Cancer - Breast cancer vaccine well tolerated and safe in clinical trial patients
Breast Cancer - Breast cancers should be staged at the time of diagnosis
Breast Cancer - Cisplatin-based treatment is effective in locally advanced breast cancer
Breast Cancer - Conference votes on breast cancer research agenda for next 2 years
Breast Cancer - Diagnosis and treatment of breast cancer improve significantly over a decade
Breast Cancer - European launch of Faslodex reported
Breast Cancer - MUC-1 in postoperative axillary drainage may indicate a poor prognosis
Breast Cancer - NDA for radiation therapy sensitizer to be reviewed by FDA panel
Breast Cancer - PTTG mRNA expression in primary breast cancer may indicate tumor aggressiveness
Breast Cancer - Paclitaxel plus vinorelbine are moderately effective in advanced breast cancer
Breast Cancer - Pathologist input is valuable to the clinician treating breast carcinoma
Breast Cancer - Pregnancies ending in abortion do not increase breast cancer risk
Breast Cancer - Serum levels of sex hormones are not associated with breast cancer risk
Breast Cancer - Simple computer program predicts who is most at risk
Breast Cancer - Study highlights misunderstanding surrounding risks, benefits of tamoxifen
Breast Cancer - Telomere shortening occurs in some normal and malignant breast tissue
Breast Cancer - Workshop report discusses partial breast irradiation
Breast Cancer Therapy - NMU-based murine model could aid search for immune-based treatment
Cancer - Study to investigate cancer rates of wafer fabrication workers
Cancer Mortality - Lung and breast are 2003 top cancer deaths in Iowa
Cancer Prevention - Screenings urged by local colon cancer survivor
Cancer Therapy - 2-Methods oxyestradiol targets the tumor cell compartment as well as angiogenesis
Cancer Therapy - Abdominal and pelvic tumors respond to stereotactic boost irradiation
Cancer Therapy - Alanine is critical to TNP-470 specificity for methionine aminopeptidase-2
Cancer Therapy - Education and research are needed to improve cancer survival in Japan
Cancer Therapy - Maxim Pharmaceuticals reacquires rights to MX2105, cancer drug candidate
Cancer Therapy - Merix Bioscience announces cancer vaccines agreement
Cancer Therapy - New Panzem formulation in phase I trial
Cancer Therapy - Oral bioavailability may make idarubicin appropriate for treating older patients
Cancer Therapy - Some patients with porphyria have an increased incidence of cancer
Cancer Therapy - Survivin knockdown reduces the clonogenic survival of sarcoma cells without p53
Carcinogens - Some bacterial toxins could cause cancer
Cell Proliferation Disorders - Positive clinical results reported on oral delivery of Neugene antisense drug
Chronic Hepatitis C - Interferon improves survival in HCV patients by negating liver-related death
Cloning - Alternative to embryonic stem cell research offered
Collaborations - Material transfer agreement signed with National Cancer Institute
Collaborations - Technology that appears to arrest uncontrolled cancer growth licensed
Colon Cancer - MTHFR C677T A1298C polymorphisms may predict risk of colon cancer
Colon Cancer - Survey reveals disconnect between knowledge, action on colon cancer screening
Colorectal Cancer - ARK5 overexpression may signal progression of colorectal cancer
Colorectal Cancer - Simple changes may help improve colorectal cancer screening rates
Complementary & Alternative Medicine - Chinese herbal medicine credited with successful lung cancer treatment
Cutaneous Lymphoma - HLA-G and IL-10 may contribute to disease severity
Diagnostics - IMPATH announces distribution agreement for QCA system
Diagnostics - LYVE-1 antibody recognizes lymphatic vessels in normal and pathological tissues
Diet & Nutrition - Boosting vitamin D levels may help prevent breast cancer, study suggests
Drug Delivery - Research aims to make smart drugs that deliver the right kind of punch
Drug Development - Conjugation with geldanamycin augments Herceptin antitumor activity
Drug Development - Epidermal growth factor receptor is a modern target for treating cancer
Drug Development - Mutant B-Raf peptide shows promise as anti-melanoma immunotherapy
Dry Mouth - Salagen 7.5 mg tablet introduced
Finance - Biotechnology company announces adoption of 10b5-1 trading plans
Finance - Cancer-drug maker reports increased net loss for fourth quarter, year
Finance - Cancer-drug maker reports increased revenues and decreased losses
Finance - ImClone gets $250M related to FDA approval of ERBITUX
Finance - Institutional investors increase stake in maker of carbohydrate-based drugs
Finance - Protein-based biopharmaceutical company reports 2003 financial results
Fitness & Wellness - New York City launches program to improve residents' health
Gastric Cancer - Laparoscopy-assisted subtotal gastrectomy is effective early gastric cancer
Gastroenterology - 5-Fluorouracil and interferon gene therapy diminish colon cancer metastasis
Gastroesophageal Cancer - Tezacitabine program to be discontinued based on phase II trial analysis
Gene Expression - NCI awards grant for gene expression research
Gene Silencing - Preclinical research focuses on gene silencing against malignancy gene
Genomics - The Genome Institute of Singapore adopts MAUI Hybridization System
Genomics - University of Southern California selects REPLI-g technology
Gynecology - Downregulated HtrA1 gene changes the phenotype of ovarian cancer
Gynecology - THY1 correlates with tumor suppression in human ovarian cancer
HIV/AIDS Cancer - Anti-HHV-8 therapy effective against multicentric Castleman disease
Hematology - Downregulated ERK protein kinase prevents myeloma from secreting VEGF
Hematology - Survivin suppression halts the growth of aggressive non-Hodgkin's lymphoma
Hodgkin Disease - HDT+ASCT not effective for patients with relapsed, refractory HD
Human Papilloma Virus - MVA-HPV-IL2 vaccine shows activity in phase II HPV clinical trial
Immunology - Aquaporin expression by lymphocytes and DCs identified, characterized
Immunology - Chemokine gene modification of dendritic cells improves antitumor activity
Intracranial Meningiomas - The dural tail of intracranial meningiomas can be seen on FLAIR images
Kaposi Sarcoma - Inflammatory cytokines may aid KSHV latency
Kaposi Sarcoma - Novel immunoassay distinguishes KS from mimics
Leukemia - Adaphostin and similar agents arrest VEGF receptor tyrosine kinases
Leukemia - St. John's wort may compromise cancer drug's ability to prevent relapse
Leukemia Therapy - Leukemic RNA-pulsed DCs induce anti-AML cytotoxic activity in vitro
Leukemia Therapy - Post-remission mobilization yields valuable DC precursors
Leukemia Therapy - RIC SCT during imatinib-induced remission can resolve CML in blast crisis
Liver Cancer - Cancer treatment given to first phase III patient
Lung Cancer - Grade 1 or 2 lung cancers are minimally invasive
Lung Cancer - Phase II study of Tarceva initiated in non-small cell lung cancer patients
Lung Cancer - Quality-of-life measures are important in clinical trials of lung cancer
Lung Cancer - Video-assisted thoracic surgery is beneficial for older patients
Lymphoma Diagnostics - Distinct immunohistochemical features of pediatric BL and DLBCL identified
Medical Marijuana - Spokespeople sought to endorse marijuana in variety of medical applications
Melanoma - Childhood exposure to UV light may begin malignant transformation of cells
Melanoma - Patient education has reduced melanoma in Australia
Melanoma - Vitiligo linked to enhanced tumor control in rats
Mesothelioma - Report says asbestos deaths growing into epidemic
Neuroscience - Irregular Id protein expression correlates with neural tumor progression
Neuroscience - Local intracerebral microinfusion improves survival in glioblastoma models
Nicotine Addiction - Rimonabant helps smokers quit while limiting post-cessation weight gain
Non-Small Cell Lung Cancer - Chemoradiation with third-generation agents is promising for NSCLC
Non-Small Cell Lung Cancer - Induction chemotherapy and radiotherapy are useful for inoperable NSCLC
Non-Small Cell Lung Cancer - Newer chemotherapy for NSCLC only slightly improves survival
Non-Small Cell Lung Cancer - Platinum agents are the usual first-line treatment for advanced NSCLC
Non-Small Cell Lung Cancer - Radiation delivery approaches for lung cancer are improved
Non-Small Cell Lung Cancer - Radiotherapy and chemotherapy are the standard of care in locally advanced NSCLC
Non-Small Cell Lung Cancer - Treatment for advanced non-small cell lung cancer is often palliative
Non-Small Cell Lung Cancer - Using novel drugs to treat non-small cell lung cancer in the elderly is feasible
Oncology - CXCR2 inhibition ends lung cancer angiogenesis and proliferation
Oncology - Cytokine gene therapy staunches murine melanoma
Oncology - Lamivudine prevents hepatitis B virus reactivation in cancer patients
Oncology - Platelet integrin alpha2 marks the efficacy of angiogenesis inhibitor E7820
Oncology - Programmed cell death 4 enhances cancer's response to chemotherapy
Oncology - Recombinant BCG DNA vaccines and gene immunotherapy treat bladder cancer
Pediatric Oncology - Researchers find less toxic treatment safe for children with cancer
Personnel - Fred Vitale named vice president, business development
Prostate Cancer - Low awareness of prostate cancer among African American men, survey shows
Prostate Cancer - New molecular-based method can assess protein expression in prostate cancer
Prostate Cancer - Patients who don't smoke live longer
Prostate Cancer - Sodium butyrate and tributyrin are effective in vivo in prostate cancer
Proteomics - Bcl-X-L helps cells resist death under hypoxic conditions
Psoriasis - License agreement signed for Interleukin 20
Public Health - Survey reveals low awareness of prostate cancer among African-American men
Radiation Sickness - ImmuneRegen gets guidance from FDA and Division of Counter Terrorism officials
Radiotherapy - Stress-responsive promoters leave cells vulnerable to radiation therapy
Skin Cancer - Aesthetic reconstruction of the nose requires careful planning
Skin Cancer - Facial reconstruction techniques after skin cancer ablation are presented
Skin Cancer - Mohs micrographic surgery is effective in managing skin cancer
Skin Cancer - Peripheral in-continuity tissue examination is useful to remove cutaneous tumors
Skin Cancer - Skin cancer often presents reconstructive challenges
Skin Cancer - Women's Dermatologic Society promotes skin cancer awareness and prevention
Skin Damage - Scientific team develops new measurement for antioxidant sun protection
Small Cell Lung Cancer - Molecular targeted therapies for small cell lung cancer are being studied
Stem Cell Research - Thalidomide targets bone marrow angiogenesis in multiple myeloma patients
Stem-Cell Transplantation - Murine marrow cellularity characterized
Testicular Cancer - Testicular cancer patients need information about sexual concerns
Uterine Cancer - Estrogen and progesterone receptors predict progression of uterine tumors
Women's Health - Women with DCIS need to be better educated about treatment choices
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