Liver Cancer

Researchers discover gene that causes liver cancer in animals

Published in Cancer Weekly, April 27th, 2004

Researchers at the University of Illinois at Chicago (UIC) have discovered a gene that spurs the growth of liver cancer.

When the gene, called Foxm1b, was deleted from liver cells in laboratory mice, the animals failed to develop tumors. Even when the researchers attempted to induce the formation of these tumors artificially, using a standard laboratory technique, the mice remained cancer-free.

"To my knowledge, this is the first time a gene has been directly linked to the growth of cancer cells in live animals," said Robert Costa, professor of biochemistry and molecular genetics in the UIC College of Medicine and the lead investigator in the...

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Source: Cancer Weekly (2004-04-27)

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