Published in Cancer Weekly, May 18th, 2004
"Recently Smac/DIABLO (second mitochondria-derived activator of caspase) has been identified as a proapoptotic protein that inhibits IAPs (inhibitors of apoptosis proteins). Smac is expressed ubiquitously in many organs, including the lung." The "expression of Smac mRNA with real-time reverse-transcription PCR" was evaluated "in 88 primary lung cancers and matched normal tissues," scientists in Japan wrote.
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