Published in Cancer Weekly, May 25th, 2004
"Telomerase is a ribonuclear protein that maintains telomere length in eukaryotic cells. Activation of the human telomerase reverse transcriptase (hTERT), the catalytic subunit of telomerase, has been implicated in cellular immortalization and may play a critical role in carcinogenesis. Prior studies in ductal carcinoma in situ (DCIS) have been small and used polymerase chain reaction (PCR)-based methods on heterogeneous tissue extracts," researchers in the United States report.
"In this study, we used in situ hybridization to determine the cell type and topographic expression...
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