Ovarian Cancer

Rb2 gene has role in ovarian carcinogenesis

Published in Cancer Weekly, May 25th, 2004

Protein expression of the tumor-suppressing gene Rb2/p130 could play a vital role in ovarian cancer, according to a study by researchers at the Sbarro Institute for Cancer Research and Molecular Medicine in the Center for Biotechnology at Temple University.

Their study was published in the May 1, 2004, issue of Clinical Cancer Research.

Antonio Giordano, MD, PhD, director of the Sbarro Institute and co-director of the Center for Biotechnology at Temple, and colleagues examined 45 primary ovarian carcinoma samples and found that 40% had a decrease or complete loss of Rb2 protein expression. Giordano discovered the Rb2 gene while working at...

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Source: Cancer Weekly (2004-05-25)

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