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Helicobacter Pylori

IL-1 genotype may determine clinical outcome of H. pylori infection

Published in Cancer Weekly, June 15th, 2004

Interleukin-1 genotypes may determine the clinical outcome of Helicobacter pylori infection.

"Helicobacter pylori infects half the world's population and is associated with serious human diseases including peptic ulcer disease and gastric neoplasia. The clinical outcome is largely dependent on the severity and distribution of the H. pylori-induced gastritis," researchers in Scotland report.

"The reasons for such variable clinical outcomes remain poorly understood. Bacterial virulence factors contribute to the pathogenicity but do not explain the divergent outcomes," wrote E.M Elomar and coworkers.

"There is...

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