Gastroenterology
Etodolac staunches colitis-induced tumors in rodent models
Published in Cancer Weekly, June 22nd, 2004
According to a study from Japan, "ulcerative colitis (UC)-associated neoplasia is one of the complications seen in patients with long-standing UC. Based on many epidemiological studies, colitis is assumed to promote colon tumorigenesis. Tumorigenesis is known to be suppressed in rodents and humans by selective cyclooxygenase-2 inhibitors."
"However, whether these drugs would serve as protective agents against UC-associated neoplasia remains unclear. Therefore, using a colitis-induced tumorigenesis rat model, we investigated the effects of etodolac, a selective cyclooxygenase-2 inhibitor, on...
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Source: Cancer Weekly (2004-06-22)
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