Urothelial Cancer

Immunohistochemistry provides reliable determination of HER-2/neu status

Published in Cancer Weekly, June 29th, 2004

Immunohistochemistry provides a highly accurate determination of HER-2/neu status in urothelial cancer patients.

"Specific treatments targeted toward oncogenes expressed in cancer cells are currently under development," scientists in France explained. "Patients with urothelial carcinomas showing HER-2/neu (human epidermal growth factor receptor 2) overexpression are candidates for such a specific treatment (trastuzumab). However, to be effective, this therapeutic approach requires an extremely reliable evaluation of HER-2/neu status in tumors."

"In order to assess the status of expression of this gene and to optimize its assessment," G. De Pinieux...

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Source: Cancer Weekly (2004-06-29)

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