Fibrinolysis
Plasma D-dimer identifies lymph node metastasis in breast cancer patients
Published in Cancer Weekly, June 29th, 2004
"Fibrin formation and removal is continuous during the development of malignancy. Plasma D-dimer is indicative of ongoing fibrinolysis, and circulating soluble fibrin polymer [thrombus precursor protein (TpP)] represents thrombogenic activity. We evaluated the relationship between plasma D-dimer and TpP levels with tumor extent and examined the use of these markers as possible predictors of lymph node metastasis in breast cancer," researchers in South Korea report.
"Preoperative plasma levels of D-dimer and TpP were measured in these 120 patients (93 breast cancer, 27 benign...
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Source: Cancer Weekly (2004-06-29)
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