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HIV/AIDS Research

HIV-related germ cell tumor not more aggressive than GCT in general population

Published in Cancer Weekly, July 6th, 2004

HIV-related germ cell tumor is not more aggressive than GCT in the general population.

"Testicular germ cell tumor (GCT) is not an AIDS-defining illness despite an increased incidence in men with HIV infection. We performed a matched case-control study comparing outcomes in HIV-positive men and the general population with GCT, using three age and stage matched controls for each case," researchers in England report.

"There was no difference in the 5-year GCT-free survival between cases and controls. However, overall survival was significantly decreased in the cases (log rank P=0.03)," said T. Powles and coworkers. "HIV was responsible for 70% of this...

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