HIV/AIDS Screening

Anal Pap smears inaccurate predictor of high-grade anal dysplasia

Published in Cancer Weekly, July 6th, 2004

Anal Pap smears are inaccurate predictors of high-grade anal dysplasia.

"We compared the pathological diagnoses obtained by anal Papanicolaou (Pap) smear with those obtained by anal biopsy or by surgical excision for 153 men who have sex with men (MSM)," wrote scientists at Harvard University.

"Analysis of these paired specimens showed that anal Pap smears were an inaccurate predictor of high-grade anal dysplasia, regardless of human immunodeficiency virus (HIV) serostatus," L.A. Panther and coworkers reported.

Investigators concluded, "The presence of any abnormal anal cytological finding indicates a potential for high-grade...

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Source: Cancer Weekly (2004-07-06)

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