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Lung Cancer

ProMune shows improved responses in lung cancer

Published in Cancer Weekly, July 6th, 2004

Coley Pharmaceutical Group, Inc., announced interim results from a randomized, multicenter phase II clinical study evaluating the effects of the company's lead TLR Therapeutic, ProMune (CPG 7909), combined with chemotherapy compared to standard chemotherapy alone in first-line treatment of advanced non-small cell lung cancer (NSCLC).

Objective tumor responses (by RECIST) in 48 patients after four cycles of taxane/platinum were documented in 42% of 31 patients given ProMune combination versus 24% of 17 patients given chemotherapy alone. The primary tumor response endpoints were supported by interim progression-free survival curves and CT tumor measurements.

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