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Small Cell Lung Cancer

IMC-BEC2 cancer vaccine trial did not meet primary endpoint

Published in Cancer Weekly, July 6th, 2004

ImClone Systems, Inc., (IMCL) and Merck, KGaA, of Darmstadt, Germany (MRK), announced that the international, randomized, phase III, clinical trial of the companies' IMC-BEC2 cancer vaccine did not meet its primary endpoint of survival.

IMC-BEC2 is an investigational anti-idiotypic monoclonal antibody that mimics GD3, a ganglioside expressed on the cell membrane of most small cell lung cancer tumors. The study was conducted in collaboration with the cooperative group European Organisation for Research and Treatment of Cancer (EORTC). The results of the clinical trial were presented by EORTC Investigator Giuseppe Giaccone, MD, PhD, department of oncology, Free University...

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